An Introduction to Tissue-Biomaterial Interactions

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An Introduction to Tissue-Biomaterial Interactions acquaints an undergraduate audience with the fundamental biological processes that influence these sophisticated, cutting-edge procedures. Chapters one through three provide more detail about the molecular-level events that happen at the tissue-implant interface, while chapters four through ten explore selected material, biological, and physiological consequences of these events. The importance of the body s wound-healing response is emphasized throughout. Specific topics covered include:Structure and properties of biomaterials ProteinsProtein-surface interactionsBlood-biomaterial interactionsInflammation and infectionThe immune systemBiomaterial responses to implantationBiomaterial surface engineeringIntimal hyperplasia and osseointegration as examples of tissue-biomaterial interactions The text also provides extensive coverage of the three pertinent interfaces between the body and the biomaterial, between the body and the living cells, and between the cells and the biomaterial that are critical in the development of tissue-engineered products that incorporate living cells within a biomaterial matrix. Ideal for a one-semester, biomedical engineering course, An Introduction to Tissue-Biomaterial Interactions provides a solid framework for understanding today s and tomorrow s implantable biomedical devices.