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Proteins act as macromolecular machinery that mediate many diverse biological processes - the molecular mechanisms of this machinery has fascinated biologists for decades. Analysis of the kinetic and thermodynamic features of these mechanisms could reveal unprecedented aspects of how the machinery function and will eventually lead to a novel understanding ...
Multistate GTPase Control Co-translational Protein Targeting
Proteins act as macromolecular machinery that mediate many diverse biological processes - the molecular mechanisms of this machinery has fascinated biologists for decades. Analysis of the kinetic and thermodynamic features of these mechanisms could reveal unprecedented aspects of how the machinery function and will eventually lead to a novel understanding of various biological processes. This dissertation comprehensively demonstrates how two universally conserved guanosine triphosphatases in the signal recognition particle and its membrane receptor maintain the efficiency and fidelity of the co-translational protein targeting process essential to all cells. A series of quantitative experiments reveal that the highly ordered and coordinated conformational states of the machinery are the key to their regulatory function. This dissertation also offers a mechanistic view of another fascinating system in which multistate protein machinery closely control critical biological processes. Written while completing graduate work at California Institute of Technology.
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125.990000 USD

Multistate GTPase Control Co-translational Protein Targeting

by Xin Zhang
Hardback
Book cover image
Electrochemical Oxidation of Glucose: Mechanisms and Applications
51.450000 USD

Electrochemical Oxidation of Glucose: Mechanisms and Applications

by Xin Zhang
Paperback / softback
Book cover image
The sources and nature of China's transformation from a traditional to modern society - accelerated in the early twentieth century by the downfall of the Qing dynasty, the advent of foreign technology and increasing commercialization - are critical issues for the study of modern China. In this book, Xin Zhang ...
Cambridge Modern China Series: Social Transformation in Modern China: The State and Local Elites in Henan, 1900-1937
The sources and nature of China's transformation from a traditional to modern society - accelerated in the early twentieth century by the downfall of the Qing dynasty, the advent of foreign technology and increasing commercialization - are critical issues for the study of modern China. In this book, Xin Zhang uses the case of local elites and the power structure of Henan province in north-central China to demonstrate how local politics first transformed local society, challenged the state and eventually influenced change across China. Rather than focusing separately on elite mobility, social mobilization or state-making, Zhang observes changes in all three categories as interrelated aspects of a single, self-generating phenomenon of social change. Zhang's application of social science theory and rich, original, empirical data, sheds light on the sources of China's modernization, political and social identity, and the shifting relationship between the state and local elites.
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130.200000 USD

Cambridge Modern China Series: Social Transformation in Modern China: The State and Local Elites in Henan, 1900-1937

by Xin Zhang
Hardback
Book cover image
Sectional Image Reconstruction in Optical Scanning Holography
61.950000 USD

Sectional Image Reconstruction in Optical Scanning Holography

by Xin Zhang
Hardback
Book cover image
Proteins act as macromolecular machinery that mediate many diverse biological processes - the molecular mechanisms of this machinery has fascinated biologists for decades. Analysis of the kinetic and thermodynamic features of these mechanisms could reveal unprecedented aspects of how the machinery function and will eventually lead to a novel understanding ...
Multistate GTPase Control Co-translational Protein Targeting
Proteins act as macromolecular machinery that mediate many diverse biological processes - the molecular mechanisms of this machinery has fascinated biologists for decades. Analysis of the kinetic and thermodynamic features of these mechanisms could reveal unprecedented aspects of how the machinery function and will eventually lead to a novel understanding of various biological processes. This dissertation comprehensively demonstrates how two universally conserved guanosine triphosphatases in the signal recognition particle and its membrane receptor maintain the efficiency and fidelity of the co-translational protein targeting process essential to all cells. A series of quantitative experiments reveal that the highly ordered and coordinated conformational states of the machinery are the key to their regulatory function. This dissertation also offers a mechanistic view of another fascinating system in which multistate protein machinery closely control critical biological processes. Written while completing graduate work at California Institute of Technology.
https://magrudy-assets.storage.googleapis.com/9781489978080.jpg
125.990000 USD

Multistate GTPase Control Co-translational Protein Targeting

by Xin Zhang
Paperback / softback
Book cover image
The book summarizes the emerging topic about the effects of SMF on biological samples ranging from single molecules, subcellular compartments, and cells to whole organisms, as well as the potential application of SMF in clinical treatment of cancer and other diseases. With the development and growing popularity of modern appliances, ...
Biological Effects of Static Magnetic Fields
The book summarizes the emerging topic about the effects of SMF on biological samples ranging from single molecules, subcellular compartments, and cells to whole organisms, as well as the potential application of SMF in clinical treatment of cancer and other diseases. With the development and growing popularity of modern appliances, including MRI in the hospitals, the potential impact of magnetic fields on human health is invoking increasing concerns. At the same time, SMF has been used in the clinical treatment of tumors and other diseases for decades. However, there are still some reservations and uncertainties about these treatments, which are largely due to the differential biological effects reported in the literature. These experimental inconsistencies are mainly caused by variations such as different magnetic field types, intensities, treatment time as well as biological samples examined. This volume will help clarify some dilemmas in this field and encourage further investigations in order to achieve a better understanding of the biological effects of SMF, aiming for a rational application of SMF in clinical therapy in the near future. The book is useful for scientists doctors, and students who are interested in magnetic fields and life sciences.
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209.990000 USD

Biological Effects of Static Magnetic Fields

by An Xu, Kevin Yarema, Xin Zhang
Hardback
Book cover image
The sources and nature of China's transformation from a traditional to modern society - accelerated in the early twentieth century by the downfall of the Qing dynasty, the advent of foreign technology and increasing commercialization - are critical issues for the study of modern China. In this book, Xin Zhang ...
Cambridge Modern China Series: Social Transformation in Modern China: The State and Local Elites in Henan, 1900-1937
The sources and nature of China's transformation from a traditional to modern society - accelerated in the early twentieth century by the downfall of the Qing dynasty, the advent of foreign technology and increasing commercialization - are critical issues for the study of modern China. In this book, Xin Zhang uses the case of local elites and the power structure of Henan province in north-central China to demonstrate how local politics first transformed local society, challenged the state and eventually influenced change across China. Rather than focusing separately on elite mobility, social mobilization or state-making, Zhang observes changes in all three categories as interrelated aspects of a single, self-generating phenomenon of social change. Zhang's application of social science theory and rich, original, empirical data, sheds light on the sources of China's modernization, political and social identity, and the shifting relationship between the state and local elites.
https://magrudy-assets.storage.googleapis.com/9780521027557.jpg
57.740000 USD

Cambridge Modern China Series: Social Transformation in Modern China: The State and Local Elites in Henan, 1900-1937

by Xin Zhang
Paperback / softback
Book cover image
The purpose of signing a tax treaty is not for its existence on paper, but for its application in practice. It must be applied and enforced by the competent authority within the domestic legal system; when it is not clear or detailed enough, the domestic law assumes the task of ...
The Law and Practice of International Tax Treaties in China
The purpose of signing a tax treaty is not for its existence on paper, but for its application in practice. It must be applied and enforced by the competent authority within the domestic legal system; when it is not clear or detailed enough, the domestic law assumes the task of interpretation and implementation - at least in a practical sense. On the other hand, these treaties act as a guideline, a benchmark or a boundary for the scope and discretion of domestic tax law; because the former has a direct effect in China and supersedes the latter if they conflict. From this point of view, the research of foreign-related income tax law cannot be isolated from tax treaties in general and specific treaties in particular, for transactions in relation to parties from such specific countries. The book provides complete and updated information for China's tax treaty law and practice, as well as all domestic laws, regulations, decrees and internal tax policies in relation to the application and implementation of tax treaties in China. It explores the underlying policies, rules and mechanisms for operating China's tax treaties either at the level of treaty law or in the domestic plane of implementation. In conjunction with the textual analysis it provides necessary guidelines or suggestion for tax planning in various business scenarios. The book views tax treaties as the starting point for solving Chinese tax issues. The related tax consequences and potential problems are also addressed.
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213.29 USD

The Law and Practice of International Tax Treaties in China

by Xin Zhang
Hardback
Book cover image
The implementation of the WTO Agreements in China has raised great international interest as a result of China's increasing importance in the world economy and the unprecedented wide range of accession commitments that China has assumed. This book researches the legal institutions, mechanisms and processes for the WTO implementation in ...
Implementation of the WTO Agreements in China
The implementation of the WTO Agreements in China has raised great international interest as a result of China's increasing importance in the world economy and the unprecedented wide range of accession commitments that China has assumed. This book researches the legal institutions, mechanisms and processes for the WTO implementation in China during more than three years of accession (up to 1 May 2005) and proposes legal solutions to improve the implementation status. The primary objective of this book is to examine the legal institutions, mechanisms, and processes for implementing the WTO Agreements in the People's Republic of China ('China' or 'the PRC'). While the WTO Agreements automatically became part of PRC law, China has always rejected their direct invoke-ability before courts for policy reasons, following the practices of major WTO Members. It is therefore argued that the key to the WTO implementation in China should be national implementing measures. Based on qualitative and quantitative analysis of three key domestic regimes: market access, domestic regulation, and dispute resolution, it concludes that from the textual perspective most WTO commitments (but especially those on market access) have been complied within the Chinese case, but that the domestic regulatory process has serious problems in terms of uniformity and reasonableness. In addition, the dispute resolution regime does not achieve the necessary degree of judicial independence mandated under the WTO Agreements. Dr Zhang's study will significantly enhance the understanding of the interaction between China's legal and regulatory reforms and the WTO implementation. It provides key information to both policy makers and practitioners who are interested in this area. Moreover, by analysing key issues in the WTO implementation process in the Chinese case, his work throws new light on important areas of international economic law.
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71.69 USD
Hardback
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