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Human Embryos and Preimplantation Genetic Technologies: Ethical, Social, and Public Policy Aspects presents the first holistic analysis of PGD and PGS as it is practiced and regulated worldwide. In addition to scientific and technical aspects, the book provides perspectives on the ethical, legal, religious, policy and social implications of global ...
Human Embryos and Preimplantation Genetic Technologies: Ethical, Social, and Public Policy Aspects
Human Embryos and Preimplantation Genetic Technologies: Ethical, Social, and Public Policy Aspects presents the first holistic analysis of PGD and PGS as it is practiced and regulated worldwide. In addition to scientific and technical aspects, the book provides perspectives on the ethical, legal, religious, policy and social implications of global assisted reproduction technologies, including in Africa, Asia, Europe, North and South America, and Australia. Chapters cover history, ethics, feminism, family dynamics, psychological and interpersonal factors, the current state of PGD and PGS in 20 different sovereign nations and religious communities, and provide an analysis of public policy concerns and future directions.
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332.72 USD

Human Embryos and Preimplantation Genetic Technologies: Ethical, Social, and Public Policy Aspects

Paperback / softback
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Advances in Genetics, Volume 104, provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of the topic. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in ...
Advances in Genetics: Volume 104
Advances in Genetics, Volume 104, provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of the topic. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, critically analyzing future directions.
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179.550000 USD

Advances in Genetics: Volume 104

Hardback
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Genome Chaos: Rethinking Genetics, Evolution, and Molecular Medicine transports readers from Mendelian Genetics to 4D-genomics, building a case for genes and genomes as distinct biological entities, and positing that the genome, rather than individual genes, defines system inheritance and represents a clear unit of selection for macro-evolution. In authoring this ...
Genome Chaos: Rethinking Genetics, Evolution, and Molecular Medicine
Genome Chaos: Rethinking Genetics, Evolution, and Molecular Medicine transports readers from Mendelian Genetics to 4D-genomics, building a case for genes and genomes as distinct biological entities, and positing that the genome, rather than individual genes, defines system inheritance and represents a clear unit of selection for macro-evolution. In authoring this thought-provoking text, Dr. Heng invigorates fresh discussions in genome theory and helps readers reevaluate their current understanding of human genetics, evolution, and new pathways for advancing molecular and precision medicine.
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196.22 USD

Genome Chaos: Rethinking Genetics, Evolution, and Molecular Medicine

by H. H. Heng
Paperback / softback
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In studying biology, one of the more difficult factors to predict is how parents' attributes will affect their children and how those children will affect their own children. Organizing and calculating those vast statistics can become extremely tedious without the proper mathematical and reproductive knowledge. Attractors and Higher Dimensions in ...
Attractors and Higher Dimensions in Population and Molecular Biology: Emerging Research and Opportunities
In studying biology, one of the more difficult factors to predict is how parents' attributes will affect their children and how those children will affect their own children. Organizing and calculating those vast statistics can become extremely tedious without the proper mathematical and reproductive knowledge. Attractors and Higher Dimensions in Population and Molecular Biology: Emerging Research and Opportunities is a collection of innovative research on the methods and applications of population logistics. While highlighting topics including gene analysis, crossbreeding, and reproduction, this book is ideally designed for academics, researchers, biologists, and mathematicians seeking current research on modeling the reproduction process of a biological population.
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173.250000 USD

Attractors and Higher Dimensions in Population and Molecular Biology: Emerging Research and Opportunities

by Gennadiy Vladimirovich Zhizhin
Hardback
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Immunotherapy of Cancer, Volume 143, the latest release in the Advances in Cancer Research series, provides invaluable information on the exciting and fast-moving field of cancer research. Contributions from leading experts in the field make this a must have update on the topic.
Immunotherapy of Cancer: Volume 143
Immunotherapy of Cancer, Volume 143, the latest release in the Advances in Cancer Research series, provides invaluable information on the exciting and fast-moving field of cancer research. Contributions from leading experts in the field make this a must have update on the topic.
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203.05 USD

Immunotherapy of Cancer: Volume 143

Hardback
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Sex Determination, Volume 134, the latest release in the Current Topics in Developmental Biology series, contains current reviews in the field of vertebrate sex determination. It covers molecular pathways of sex determination in genetic and environmental species and encompasses both sex determination of somatic lineages and commitment of germ cells ...
Sex Determination in Vertebrates: Volume 134
Sex Determination, Volume 134, the latest release in the Current Topics in Developmental Biology series, contains current reviews in the field of vertebrate sex determination. It covers molecular pathways of sex determination in genetic and environmental species and encompasses both sex determination of somatic lineages and commitment of germ cells to male or female fate. Chapters in this new release cover, amongst other topics, Mapping the Sox9 Enhancer Elements, Epigenetic Regulation of Sex Determination, Evolution and Management of Sex Chromosomes, Regulation of Germ Cell Sex Identity in Medaka, Control of Sex Determination in Zebrafish, Sexually Dimorphic Germ Cell Identity in Mammals, and more.
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220.500000 USD

Sex Determination in Vertebrates: Volume 134

Hardback
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This textbook helps you to prepare for your next exams and practical courses by combining theory with virtual lab simulations. The Labster Virtual Lab Experiments series gives you a unique opportunity to apply your newly acquired knowledge in a learning game that simulates exciting laboratory experiments. Try out different techniques ...
Labster Virtual Lab Experiments: Basic Biochemistry
This textbook helps you to prepare for your next exams and practical courses by combining theory with virtual lab simulations. The Labster Virtual Lab Experiments series gives you a unique opportunity to apply your newly acquired knowledge in a learning game that simulates exciting laboratory experiments. Try out different techniques and work with machines that you otherwise wouldn't have access to.In this book, you'll learn the fundamental concepts of basic biochemistry focusing on: Ionic and Covalent Bonds Introduction to Biological Macromolecules Carbohydrates Enzyme Kinetics In each chapter, you'll be introduced to one virtual lab simulation and a true-to-life challenge. Following a theory section, you'll be able to play the relevant simulation that includes quiz questions to reinforce your understanding of the covered topics. 3D animations will show you molecular processes not otherwise visible to the human eye. If you have purchased a printed copy of this book, you get free access to five simulations for the duration of six months. If you're using the e-book version, you can sign up and buy access to the simulations at www.labster.com/springer. If you like this book, try out other topics in this series, including Basic Biology , Basic Genetics , and Genetics of Human Diseases .
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42.64 USD

Labster Virtual Lab Experiments: Basic Biochemistry

by Frederik Clauson-Kaas, Dewi Ayu Kencana Ungu, Sarah Stauffer, Wilko Duprez, Aaron Gardner
Mixed media product
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The study of emotions has rapidly expanded in recent decades, incorporating interdisciplinary research on the genetic underpinnings and neural mechanisms of emotion. This has involved a wide range of methods from as varied fields as behavioral genetics, molecular biology, and cognitive neuroscience, and has allowed researchers to start addressing complex ...
Genes, brain, and emotions: Interdisciplinary and Translational Perspectives
The study of emotions has rapidly expanded in recent decades, incorporating interdisciplinary research on the genetic underpinnings and neural mechanisms of emotion. This has involved a wide range of methods from as varied fields as behavioral genetics, molecular biology, and cognitive neuroscience, and has allowed researchers to start addressing complex multi-level questions such as: what is the role of genes in individual differences in emotions and emotional vulnerability to psychopathology, and what are the neural mechanisms through which genes and experience shape these emotion? Genes, Brain, and Emotions: Interdisciplinary and translational perspectives offers a comprehensive account of this interdisciplinary field of research, bridging psychology, genetics, and neuroscience, with rich sections dedicated to methods, cognitive and biological mechanisms, and psychopathology. Written by leading researchers who have each inspired new research directions and innovated methods and concepts, this book will be of interest to anyone working or studying in the field of affective science, whether they be behavioural geneticists, psychologists and psychiatrists, or cognitive neuroscientists.
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99.750000 USD
Hardback
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Advances in Phytonanotechnology: From Synthesis to Application guides readers through various applications of nanomaterials on plants by presenting the latest research related to nanotechnology and nanomaterials on plant systems. The book focuses on the effects of these applications on plant morphology, physiology, biochemistry, ecology and genetics. Sections cover the impact ...
Advances in Phytonanotechnology: From Synthesis to Application
Advances in Phytonanotechnology: From Synthesis to Application guides readers through various applications of nanomaterials on plants by presenting the latest research related to nanotechnology and nanomaterials on plant systems. The book focuses on the effects of these applications on plant morphology, physiology, biochemistry, ecology and genetics. Sections cover the impact on plant yield, techniques, a review of positive and negative impacts, and an overview of current policies regarding the use of nanotechnology on plants. Additionally, the book offers insights into the appropriate application of nanoscience to plants and crops for improved outcome and an exploration of their bioavailability and toxicity in the environment.
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210.000000 USD

Advances in Phytonanotechnology: From Synthesis to Application

Paperback / softback
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This textbook helps you to prepare for your next exams and practical courses by combining theory with virtual lab simulations. The Labster Virtual Lab Experiments series gives you a unique opportunity to apply your newly acquired knowledge in a learning game that simulates exciting laboratory experiments. Try out different techniques ...
Labster Virtual Lab Experiments: Genetics of Human Diseases
This textbook helps you to prepare for your next exams and practical courses by combining theory with virtual lab simulations. The Labster Virtual Lab Experiments series gives you a unique opportunity to apply your newly acquired knowledge in a learning game that simulates exciting laboratory experiments. Try out different techniques and work with machines that you otherwise wouldn't have access to.In this book, you'll learn the fundamental concepts of the genetics of human diseases focusing on: Monogenic Disorders - Cytogenetics - Medical Genetics - Viral Gene Therapy In each chapter, you'll be introduced to one virtual lab simulation and a true-to-life challenge. Following a theory section, you'll be able to play the relevant simulation that includes quiz questions to reinforce your understanding of the covered topics. 3D animations will show you molecular processes not otherwise visible to the human eye. If you have purchased a printed copy of this book, you get free access to five simulations for the duration of six months. If you're using the e-book version, you can sign up and buy access to the simulations at www.labster.com/springer. If you like this book, try out other topics in this series, including Basic Biology , Basic Genetics , and Basic Biochemistry .
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42.64 USD

Labster Virtual Lab Experiments: Genetics of Human Diseases

by Dewi Ayu Kencana Ungu, Philip Wismer, Lindsay Petley-Ragan, Sarah Stauffer, Aaron Gardner
Mixed media product
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After a chance encounter with an obscure Middle Eastern red, journalist Kevin Begos embarks on a ten-year journey to seek the origins of wine. What he unearths is a whole world of forgotten grapes, each with distinctive tastes and aromas, as well as the archaeologists, geneticists, chemists - even a ...
Tasting the Past: The Science of Flavor and the Search for the Origins of Wine
After a chance encounter with an obscure Middle Eastern red, journalist Kevin Begos embarks on a ten-year journey to seek the origins of wine. What he unearths is a whole world of forgotten grapes, each with distinctive tastes and aromas, as well as the archaeologists, geneticists, chemists - even a paleobotanist - who are deciphering wine down to molecules of flavour. We meet a young scientist who sets out to decode the DNA of every single wine grape in the world; a researcher who seeks to discover the wines that Caesar and Cleopatra drank; and an academic who has spent decades analysing wine remains to pinpoint ancient vineyards. Science illuminates wine in ways no critic can, and it has demolished some of the most sacred dogmas of the industry: for example, well-known French grapes aren't especially noble. We travel with Begos along the original wine routes - starting in the Caucasus Mountains, where wine grapes were first domesticated eight thousand years ago; then down to Israel and across the Mediterranean to Greece, Italy, and France; and finally to America where vintners are just now beginning to make distinctive wines from a new generation of local grapes. Imagine the wine grape version of heirloom vegetables or craft beer, or better yet, taste it: Begos offers readers drinking suggestions that go far beyond the endless bottles of Chardonnay and Merlot found in most stores and restaurants. In this viticultural detective story wine geeks and history lovers alike will discover new tastes and flavours to savour.
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17.800000 USD

Tasting the Past: The Science of Flavor and the Search for the Origins of Wine

by Kevin Begos
Paperback / softback
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Glycans play essential roles in diverse biological and etiological processes and their structural complexity endow various functions. The glycome is the entire set of glycans produced by an individual organism. As the glycan microarray emerged, a good amount of knowledge has been obtained in understanding the functions of glycans. However, ...
Synthetic Glycomes
Glycans play essential roles in diverse biological and etiological processes and their structural complexity endow various functions. The glycome is the entire set of glycans produced by an individual organism. As the glycan microarray emerged, a good amount of knowledge has been obtained in understanding the functions of glycans. However, limited accessibility of glycans is a major obstacle to the functional glycomics study. Although isolation from biology samples provided some structures, the low abundance of glycans obtained and the difficulty in complete structural assignment restricted the subsequent assay. To circumvent this limitation, many synthetic strategies, including chemical, enzymatic and chemo-enzymatic ones have been developed to make libraries of structurally defined complex glycans available. The glycans provided by these techniques combined with high-throughput glycoarray techniques have broadened and deepened our understanding about functional glycomics. The aim of this book is to provide a comprehensive review of the current state of the synthetic glycome and a brief introduction of the application of the synthetic glycome in glycoarray assay. Accordingly, synthetic strategies toward generating glycans with comprehensive structures as well as the glycoarrays to unveil the glycan functions are described in this book.
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288.36 USD

Synthetic Glycomes

Hardback
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'Mind-blowing ... It is a hugely important book ... His story is crucial' Matt Ridley, The Times One of the world's top behavioural geneticists argues that we need a radical rethink about what makes us who we are The blueprint for our individuality lies in the 1% of DNA that ...
Blueprint: How DNA Makes Us Who We Are
'Mind-blowing ... It is a hugely important book ... His story is crucial' Matt Ridley, The Times One of the world's top behavioural geneticists argues that we need a radical rethink about what makes us who we are The blueprint for our individuality lies in the 1% of DNA that differs between people. Our intellectual capacity, our introversion or extraversion, our vulnerability to mental illness, even whether we are a morning person - all of these aspects of our personality are profoundly shaped by our inherited DNA differences. In Blueprint, Robert Plomin, a pioneer in the field of behavioural genetics, draws on a lifetime's worth of research to make the case that DNA is the most important factor shaping who we are. Our families, schools and the environment around us are important, but they are not as influential as our genes. This is why, he argues, teachers and parents should accept children for who they are, rather than trying to mould them in certain directions. Even the environments we choose and the signal events that impact our lives, from divorce to addiction, are influenced by our genetic predispositions. Now, thanks to the DNA revolution, it is becoming possible to predict who we will become, at birth, from our DNA alone. As Plomin shows us, these developments have sweeping implications for how we think about parenting, education, and social mobility. A game-changing book by a leader in the field, Blueprint shows how the DNA present in the single cell with which we all begin our lives can impact our behaviour as adults.
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15.75 USD

Blueprint: How DNA Makes Us Who We Are

by Robert Plomin
Paperback / softback
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This is an introductory text and laboratory manual to be used primarily in undergraduate courses. It is also useful for graduate students and research scientists who require an introduction to the theory and methods of nanopore sequencing. The book has clear explanations of the principles of this emerging technology, together ...
Nanopore Sequencing: An Introduction
This is an introductory text and laboratory manual to be used primarily in undergraduate courses. It is also useful for graduate students and research scientists who require an introduction to the theory and methods of nanopore sequencing. The book has clear explanations of the principles of this emerging technology, together with instructional material written by experts that describes how to use a MinION nanopore instrument for sequencing in research or the classroom.At Harvard University the book serves as a textbook and lab manual for a university laboratory course designed to intensify the intellectual experience of incoming undergraduates while exploring biology as a field of concentration. Nanopore sequencing is an ideal topic as a path to encourage students about the range of courses they will take in Biology by pre-emptively addressing the complaint about having to take a course in Physics or Maths while majoring in Biology. The book addresses this complaint by concretely demonstrating the range of topics - from electricity to biochemistry, protein structure, molecular engineering, and informatics - that a student will have to master in subsequent courses if he or she is to become a scientist who truly understands what his or her biology instrument is measuring when investigating biological phenomena.
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102.900000 USD

Nanopore Sequencing: An Introduction

by David W Deamer, Daniel Branton
Hardback
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Chromatin Signaling and Neurological Disorders, Volume Seven, explores our current understanding of how chromatin signaling regulates access to genetic information, and how their aberrant regulation can contribute to neurological disorders. Researchers, students and clinicians will not only gain a strong grounding on the relationship between chromatin signaling and neurological disorders, ...
Chromatin Signaling and Neurological Disorders: Volume 12
Chromatin Signaling and Neurological Disorders, Volume Seven, explores our current understanding of how chromatin signaling regulates access to genetic information, and how their aberrant regulation can contribute to neurological disorders. Researchers, students and clinicians will not only gain a strong grounding on the relationship between chromatin signaling and neurological disorders, but they'll also discover approaches to better interpret and employ new diagnostic studies and epigenetic-based therapies. A diverse range of chapters from international experts speaks to the basis of chromatin and epigenetic signaling pathways and specific chromatin signaling factors that regulate a range of diseases. In addition to the basic science of chromatin signaling factors, each disease-specific chapter speaks to the translational or clinical significance of recent findings, along with important implications for the development of epigenetics-based therapeutics. Common themes of translational significance are also identified across disease types, as well as the future potential of chromatin signaling research.
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230.35 USD

Chromatin Signaling and Neurological Disorders: Volume 12

Hardback
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From pathology to treatment, MicroRNAs in Diseases and Disorders highlights the role of microRNAs (miRNAs) in the development and progression of a variety of diseases, including cancer, neurological disease, endocrine disease and autoimmune disease, and underscores the utilization of miRNA targets in the treatment of these conditions. Providing a comprehensive ...
MicroRNAs in Diseases and Disorders: Emerging Therapeutic Targets
From pathology to treatment, MicroRNAs in Diseases and Disorders highlights the role of microRNAs (miRNAs) in the development and progression of a variety of diseases, including cancer, neurological disease, endocrine disease and autoimmune disease, and underscores the utilization of miRNA targets in the treatment of these conditions. Providing a comprehensive account, this book also includes the identification of miRNAs as diagnostic and prognostic biomarkers for disease, as well as evaluates translational value from clinical trials using synthesized and functionalized miRNA mimics and inhibitors. With a global contribution list and chapters from leading experts across the field, MicroRNAs in Diseases and Disorders is an invaluable reference to miRNA researchers and health professionals in a variety of disease areas in government, academia and industry. The book will also appeal to pharmaceutical and medicinal chemists with an interest in miRNA targeting therapeutics, as well as to advanced students in chemical biology and drug discovery.
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305.42 USD

MicroRNAs in Diseases and Disorders: Emerging Therapeutic Targets

Hardback
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What if you could have your own real dragon? While that might seem like just a fantasy, today cutting-edge science has brought us to the point where it might really be possible. This book looks into the possibilities of making living, fire-breathing dragons. The world has been fascinated with dragons ...
How To Build A Dragon Or Die Trying: A Satirical Look At Cutting-edge Science
What if you could have your own real dragon? While that might seem like just a fantasy, today cutting-edge science has brought us to the point where it might really be possible. This book looks into the possibilities of making living, fire-breathing dragons. The world has been fascinated with dragons for thousands of years. Fictional dragons still have a firm place in pop culture, such as Smaug from The Hobbit as well as the dragons in Game of Thrones and in the How to Train Your Dragon movies. This new book discusses using powerful technologies such as CRISPR gene editing, stem cells, and bioengineering to make real dragons. It also goes through what useful information we can learn from animals such as Pteranodons and amazing present-day creatures in our quest to build actual dragons. The book goes on to discuss the possibility of building other mythical creatures such as unicorns and mermaids. Overall, How to Build A Dragon is also meant as a satirical look at cutting-edge science, and it pokes fun at science hype. Anyone who is interested in dragons or cutting-edge science will enjoy this book! It is written in a humorous, approachable way making science fun and easy to understand, including for young adults.The author is well-known scientist Paul Knoepfler who is familiar to the public for his science, his blog The Niche, and his frequent contributions to lay stories on new science concepts such as stem cells and CRISPR. He also is known for his TED talk on designer babies with more than 1.3 million views, and his two books - . The co-author, his daughter Julie Knoepfler, is a high school student interested in science and writing. She has her own blog on literary and film analysis, and enjoys taking a humorous look at culture through writing.
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71.400000 USD

How To Build A Dragon Or Die Trying: A Satirical Look At Cutting-edge Science

by Julie Knoepfler, Paul Knoepfler
Hardback
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As read on RADIO 4'S BOOK OF THE WEEK 'An exciting introduction to a little-known microscopic universe and to a talented new writer.' Sunday Times How does our diet affect our skin? What makes the skin age? And why can't we tickle ourselves? Providing a cover for our delicate and ...
The Remarkable Life of the Skin: An intimate journey across our surface
As read on RADIO 4'S BOOK OF THE WEEK 'An exciting introduction to a little-known microscopic universe and to a talented new writer.' Sunday Times How does our diet affect our skin? What makes the skin age? And why can't we tickle ourselves? Providing a cover for our delicate and intricate bodies, the skin is our largest and fastest growing organ. We see it, touch it and live in it every day. It's a habitat for a mesmerizingly complex world of micro-organisms and physical functions that are vital to our health and our survival. It's also one of the first things people see about us and is crucial to our sense of identity. And yet how much do we really know about it? Through the lenses of science, sociology and history, Dr Monty Lyman leads us on a journey across our most underrated and unexplored organ and reveals how the skin is far stranger and more complex than you've ever imagined.
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34.12 USD

The Remarkable Life of the Skin: An intimate journey across our surface

by Monty Lyman
Hardback
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This volume provides relevant synthetic strategies, incorporation, and applications of non-natural nucleic acids. Chapters detail monomer synthesis, oligomer synthesis/construction, and applications allowing researchers to explore and determine which methodology or methodologies are relevant to their needs. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions ...
Non-Natural Nucleic Acids: Methods and Protocols
This volume provides relevant synthetic strategies, incorporation, and applications of non-natural nucleic acids. Chapters detail monomer synthesis, oligomer synthesis/construction, and applications allowing researchers to explore and determine which methodology or methodologies are relevant to their needs. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Non-Natural Nucleic Acids: Methods and Protocols aims to serve as a guide for researchers exploring their own inquiries and to provide a springboard for new endeavors.
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230.990000 USD

Non-Natural Nucleic Acids: Methods and Protocols

Hardback
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Pharmacoepigenetics, Volume Eleven provides a comprehensive volume on the role of epigenetics and epigenomics in drug discovery and development, providing a detailed, but accessible, view of the field, from basic principles, to applications in disease therapeutics. Leading international researchers from across academia, clinical settings and the pharmaceutical industry discuss the ...
Pharmacoepigenetics: Volume 10
Pharmacoepigenetics, Volume Eleven provides a comprehensive volume on the role of epigenetics and epigenomics in drug discovery and development, providing a detailed, but accessible, view of the field, from basic principles, to applications in disease therapeutics. Leading international researchers from across academia, clinical settings and the pharmaceutical industry discuss the influence of epigenetics and epigenomics in human pathology, epigenetic biomarkers for disease prediction, diagnosis, and treatment, current epigenetic drugs, and the application of epigenetic procedures in drug development. Throughout the book, chapter authors offer a balanced and objective discussion of the future of pharmacoepigenetics and its crucial contribution to the growth of precision and personalized medicine.
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210.000000 USD

Pharmacoepigenetics: Volume 10

Hardback
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This thought-provoking publication covers a wide-range of innovative areas of research and technologies that are unlocking groundbreaking new potentials in science. It contains important scientific information gleaned from the lectures of some of the world's experts in their respective fields. The book offers 'exceptional scientific insights, oftentimes addressing challenges before ...
Promise Of Science, The: Essays And Lectures From Modern Scientific Pioneers
This thought-provoking publication covers a wide-range of innovative areas of research and technologies that are unlocking groundbreaking new potentials in science. It contains important scientific information gleaned from the lectures of some of the world's experts in their respective fields. The book offers 'exceptional scientific insights, oftentimes addressing challenges before they are even recognized as questions. Chronicling the revolutionary ideas of Nobel Laureates, winners of Wolf Prize, US National Medal of Science and other notable scientists.
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92.400000 USD

Promise Of Science, The: Essays And Lectures From Modern Scientific Pioneers

Hardback
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Biology of Aging, Second Edition presents the biological principles that have led to a new understanding of the causes of aging and describes how these basic principles help one to understand the human experience of biological aging, longevity, and age-related disease. Intended for undergraduate biology students, it describes how the ...
Biology of Aging
Biology of Aging, Second Edition presents the biological principles that have led to a new understanding of the causes of aging and describes how these basic principles help one to understand the human experience of biological aging, longevity, and age-related disease. Intended for undergraduate biology students, it describes how the rate of biological aging is measured; explores the mechanisms underlying cellular aging; discusses the genetic pathways that affect longevity in various organisms; outlines the normal age-related changes and the functional decline that occurs in physiological systems over the lifespan; and considers the implications of modulating the rate of aging and longevity. The book also includes end-of-chapter discussion questions to help students assess their knowledge of the material. Roger McDonald received his Ph.D. from the University of Southern California and is Professor Emeritus in the Department of Nutrition at the University of California, Davis. Dr. McDonald's research focused on mechanisms of cellular aging and the interaction between nutrition and aging. His research addressed two key topics in the field: the relationship between dietary restriction and lifespan, and the effect of aging on circadian rhythms and hypothalamic regulation. You can contact Dr. McDonald at rbmcdonald@ucdavis.edu. Related Titles Ahmad, S. I., ed. Aging: Exploring a Complex Phenomenon (ISBN 978-1-1381-9697-1) Moody, H. R. & J. Sasser. Gerontology: The Basics (ISBN 978-1-1387-7582-4) Timiras, P. S. Physiological Basis of Aging and Geriatrics (ISBN 978-0-8493-7305-3)
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93.83 USD

Biology of Aging

by Roger B. McDonald
Paperback / softback
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Epigenetics and Regeneration compiles the first foundational reference on epigenetic mechanisms governing tissue development, repair, homeostasis, and regeneration, as well as pathways to employ these mechanisms in clinical practice and translational science. In this book, life science researchers, clinicians, and students will discover an interdisciplinary resource bringing together common themes ...
Epigenetics and Regeneration: Volume 11
Epigenetics and Regeneration compiles the first foundational reference on epigenetic mechanisms governing tissue development, repair, homeostasis, and regeneration, as well as pathways to employ these mechanisms in clinical practice and translational science. In this book, life science researchers, clinicians, and students will discover an interdisciplinary resource bringing together common themes in the field, background overviews, research methods, recent advances, and opportunities for drug discovery. Throughout this volume, special attention is paid to pre-clinical and first clinical studies aimed at increasing the regenerative potential of damaged tissues by epigenetic drugs, as well as innovative, discipline spanning strategies to enhance cell reprogramming. As an all-inclusive, evidence-based volume, Epigenetics and Regeneration will stimulate discussion and boost new research in this fascinating and impactful area of translational epigenetics.
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210.000000 USD

Epigenetics and Regeneration: Volume 11

Hardback
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Companion and Complementary Diagnostics: From Biomarker Discovery to Clinical Implementation provides readers with in-depth insights into the individual steps in the development of companion diagnostic assays, from the early biomarker discovery phase straight through to final regulatory approval. Further, the clinical implementation of companion diagnostic testing in the clinic is ...
Companion and Complementary Diagnostics: From Biomarker Discovery to Clinical Implementation
Companion and Complementary Diagnostics: From Biomarker Discovery to Clinical Implementation provides readers with in-depth insights into the individual steps in the development of companion diagnostic assays, from the early biomarker discovery phase straight through to final regulatory approval. Further, the clinical implementation of companion diagnostic testing in the clinic is also discussed. As the development of predictive or selective biomarker assays linked to specific drugs is substantially increasing, this book offers comprehensive information on this quickly-evolving area of biomedicine. It is an essential resource for those in academic institutions, hospitals and pharma, and biotech and diagnostic commercial companies.
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157.500000 USD

Companion and Complementary Diagnostics: From Biomarker Discovery to Clinical Implementation

by Jan Trost Jorgensen
Paperback / softback
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DNA. The double helix; the blueprint of life; and, during the early 1950s, a baffling enigma that could win a Nobel Prize. Everyone knows that James Watson and Francis Crick discovered the double helix. In fact, they clicked into place the last piece of a huge jigsaw puzzle that other ...
Unravelling the Double Helix: The Lost Heroes of DNA
DNA. The double helix; the blueprint of life; and, during the early 1950s, a baffling enigma that could win a Nobel Prize. Everyone knows that James Watson and Francis Crick discovered the double helix. In fact, they clicked into place the last piece of a huge jigsaw puzzle that other researchers had assembled over decades. Researchers like Maurice Wilkins (the 'Third Man of DNA') and Rosalind Franklin, famously demonised by Watson. Not forgetting the 'lost heroes' who fought to prove that DNA is the stuff of genes, only to be airbrushed out of history. In Unravelling the Double Helix, Professor Gareth Williams sets the record straight. He tells the story of DNA in the round, from its discovery in pus-soaked bandages in 1868 to the aftermath of Watson's best-seller The Double Helix a century later. You don't need to be a scientist to enjoy this book. It's a page-turner that unfolds like a detective story, with suspense, false leads and treachery, and a fabulous cast of noble heroes and back-stabbing villains. But beware: some of the science is dreadful, and the heroes and villains may not be the ones you expect.
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23.62 USD

Unravelling the Double Helix: The Lost Heroes of DNA

by Gareth Williams
Paperback / softback
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Introductory text for students of genetics is general and the students of agronomy as the book gives numerous agronomic applications.
Genetic Engineering and Biotechnology: Concepts, Methods and Agronomic Applications
Introductory text for students of genetics is general and the students of agronomy as the book gives numerous agronomic applications.
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204.750000 USD

Genetic Engineering and Biotechnology: Concepts, Methods and Agronomic Applications

by Yves Tourte
Hardback
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Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the ...
Cell Biology and Translational Medicine, Volume 5: Stem Cells: Translational Science to Therapy
Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature's longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the fifth volume of a continuing series.
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188.990000 USD

Cell Biology and Translational Medicine, Volume 5: Stem Cells: Translational Science to Therapy

Hardback
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Transgenerational Epigenetics, Second Edition, offers the only up-to-date, comprehensive analysis of the inheritance of epigenetic phenomena between generations with an emphasis on human disease relevance, drug discovery, and next steps in clinical translation. International experts discuss mechanisms of epigenetic inheritance, its expression in animal and plant models, and how human ...
Transgenerational Epigenetics: Volume 13
Transgenerational Epigenetics, Second Edition, offers the only up-to-date, comprehensive analysis of the inheritance of epigenetic phenomena between generations with an emphasis on human disease relevance, drug discovery, and next steps in clinical translation. International experts discuss mechanisms of epigenetic inheritance, its expression in animal and plant models, and how human ailments, such as metabolic disorders and cardiovascular disease are influenced by transgenerational epigenetic inheritance. Where evidence is sufficient, epigenetic clinical interventions are proposed that may help prevent or reduce the severity of disease before offspring are born. This edition has been thoroughly revised in each disease area, featuring newly researched actors in epigenetic regulation, including long noncoding RNA in addition to histone modifications and DNA methylation. Therapeutic pathways in treating cancer and extending human longevity are also considered, as are current debates and future directions for research.
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210.000000 USD

Transgenerational Epigenetics: Volume 13

Paperback / softback
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Few people have done as much to change how we view the world as Charles Darwin. Yet On the Origin of Species is more cited than read, and parts of it are even considered outdated. In some ways, it has been consigned to the nineteenth century. In The Theory That ...
The Theory That Changed Everything: On the Origin of Species as a Work in Progress
Few people have done as much to change how we view the world as Charles Darwin. Yet On the Origin of Species is more cited than read, and parts of it are even considered outdated. In some ways, it has been consigned to the nineteenth century. In The Theory That Changed Everything, the renowned cognitive scientist Philip Lieberman demonstrates that there is no better guide to the world's living-and still evolving-things than Darwin and that the phenomena he observed are still being explored at the frontiers of science. In an exploration that ranges from Darwin's transformative trip aboard the Beagle to Lieberman's own sojourns in the remotest regions of the Himalayas, this book relates fresh, contemporary findings to the major concepts of Darwinian theory, which transcends natural selection. Drawing on his own research into the evolution of human linguistic and cognitive abilities, Lieberman explains the paths that adapted human anatomy to language. He demystifies the role of recently identified transcriptional and epigenetic factors encoded in DNA, explaining how nineteenth-century Swedish famines alternating with years of plenty caused survivors' grandchildren to die many years short of their life expectancy. Lieberman is equally at home decoding supermarket shelves and climbing with the Sherpas as he discusses how natural selection explains features from lactose tolerance to ease of breathing at Himalayan altitudes. With conversational clarity and memorable examples, Lieberman relates the insights that led to groundbreaking discoveries in both Darwin's time and our own while asking provocative questions about what Darwin would have made of controversial issues today, such as GMOs, endangered species, and the God question.
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32.40 USD

The Theory That Changed Everything: On the Origin of Species as a Work in Progress

by Philip Lieberman
Paperback / softback
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SHORTLISTED FOR THE 2018 BAILLIE GIFFORD PRIZE FOR NON-FICTION She Has Her Mother's Laugh presents a profoundly original perspective on what we pass along from generation to generation. Charles Darwin played a crucial part in turning heredity into a scientific question, and yet he failed spectacularly to answer it. The ...
She Has Her Mother's Laugh: The Story of Heredity, Its Past, Present and Future
SHORTLISTED FOR THE 2018 BAILLIE GIFFORD PRIZE FOR NON-FICTION She Has Her Mother's Laugh presents a profoundly original perspective on what we pass along from generation to generation. Charles Darwin played a crucial part in turning heredity into a scientific question, and yet he failed spectacularly to answer it. The birth of genetics in the early 1900s seemed to do precisely that. Gradually, people translated their old notions about heredity into a language of genes. As the technology for studying genes became cheaper, millions of people ordered genetic tests to link themselves to missing parents, to distant ancestors, to ethnic identities . . . But, award-winning science writer Carl Zimmer argues, heredity isn't just about genes that pass from parent to child. Heredity continues within our own bodies, as a single cell gives rise to trillions of cells that make up our bodies. We say we inherit genes from our ancestors but we inherit other things that matter as much or more to our lives, from microbes to technologies we use to make life more comfortable. We need a new definition of what heredity is and, through Carl Zimmer's lucid exposition and storytelling, this resounding tour de force delivers it. Weaving together historical and current scientific research, his own experience with his two daughters, and the kind of original reporting expected of one of the world's best science journalists, Zimmer ultimately unpacks urgent bioethical quandaries arising from new biomedical technologies, but also long-standing presumptions about who we really are and what we can pass on to future generations.
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20.48 USD

She Has Her Mother's Laugh: The Story of Heredity, Its Past, Present and Future

by Carl Zimmer
Paperback / softback
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