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Easily networked throughout your school, each ActiveTeach CD-ROM includes site licences of: ActiveBook - a fully interactive digital version of the Students' Book that lets you zoom into specific areas of each page captivating videos - a wide selection of specially commissioned How Science Works videos and news clips show ...
Edexcel A Level Science: A2 Chemistry ActiveTeach: Edexcel A Level Science: A2 Chemistry ActiveTeach CDROM ActiveTeach
Easily networked throughout your school, each ActiveTeach CD-ROM includes site licences of: ActiveBook - a fully interactive digital version of the Students' Book that lets you zoom into specific areas of each page captivating videos - a wide selection of specially commissioned How Science Works videos and news clips show science in context and help you bring the universe to your classroom! engaging animations - to help you illustrate dynamic and abstract concepts past questions and worked examples - provide plenty of practice ahead of the examination. thousands of interactive activities - to help consolidate learning. written and audio glossary - provides support for all abilities. This unique interactive resource is only available from Pearson and has already revolutionised teaching at GCSE and KS3. Visit our Edexcel GCE Sciences ActiveTeach page to view sample screenshots and find out more!
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881.49 USD
CD-ROM
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The potential health hazards that might arise from the presence of organic substances in water are a matter of increasing concern to the water industry, environmentalists and the general public alike. This comprehensive reference draws together and systematises the vast body of information available on the occurrence and determination of ...
Organic Compounds in Natural Waters: Analysis and Determination
The potential health hazards that might arise from the presence of organic substances in water are a matter of increasing concern to the water industry, environmentalists and the general public alike. This comprehensive reference draws together and systematises the vast body of information available on the occurrence and determination of organic substances in natural waters. Organic Compounds in Natural Waters provides a comprehensive description of organic substances in waters. Methods are provided in broad outline, with guidance on their applicability, their comparative advantages and disadvantages, possible interferences, sensitivity and detection levels. The book is an essential reference for analytical chemists working in industry, water utilities, government, non government organisations and regulatory agencies and environmental/analytical consultants.
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100.32 USD
Hardback
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Nanostructured electrode materials have exhibited unrivaled electrochemical properties in creating elite supercapacitors. Morphology Design Paradigm for Supercapacitors presents the latest advances in the improvement of supercapacitors due to the incorporation of nanomaterials into the design; from zero-dimensional to three-dimensional, and microporous to mesoporous. Coverage includes basic comprehension of capacitive practices ...
Morphology Design Paradigms for Supercapacitors
Nanostructured electrode materials have exhibited unrivaled electrochemical properties in creating elite supercapacitors. Morphology Design Paradigm for Supercapacitors presents the latest advances in the improvement of supercapacitors due to the incorporation of nanomaterials into the design; from zero-dimensional to three-dimensional, and microporous to mesoporous. Coverage includes basic comprehension of capacitive practices at sub-atomic and nanoscales to enhance device performance for an extensive assortment of potential applications, including customer electronics, wearable gadgets, hybrid electric vehicles, stationary and industrial frameworks. Key Features: Provides readers with a clear understanding of the execution of these materials as electrodes in electrochemical supercapacitors. Covers recent material designs and an extensive scope of electrode materials such as 0D to 3D. Explores recent nanostructured system material designs that have been created and tested in supercapacitor configurations. Considers microporous to mesoporous supercapacitor electrode materials. Features the impact of nanostructures on the properties of supercapacitors; including specific capacitance, cycle stability, and rate capability.
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209.950000 USD
Hardback
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Among electrode materials, inorganic materials have received vast consideration owing to their redox chemistry, chemical stability, high electrochemical performance, and high-power applications. These exceptional properties enable inorganic-based materials to find application in high-performance energy conversion and storage. The current advances in nanotechnology have uncovered novel inorganic materials by various strategies ...
Inorganic Nanomaterials for Supercapacitor Design
Among electrode materials, inorganic materials have received vast consideration owing to their redox chemistry, chemical stability, high electrochemical performance, and high-power applications. These exceptional properties enable inorganic-based materials to find application in high-performance energy conversion and storage. The current advances in nanotechnology have uncovered novel inorganic materials by various strategies and their different morphological features may serve as a rule for future supercapacitor electrode design for efficient supercapacitor performance. Inorganic Nanomaterials for Supercapacitor Design depicts the latest advances in inorganic nanomaterials for supercapacitor energy storage devices. Key Features: Provides an overview on the supercapacitor application of inorganic-based materials. Describes the fundamental aspects, key factors, advantages, and challenges of inorganic supercapacitors. Presents up-to-date coverage of the large, rapidly growing, and complex literature on inorganic supercapacitors. Surveys current applications in supercapacitor energy storage. Explores the new aspects of inorganic materials and next-generation supercapacitor systems.
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209.950000 USD
Hardback
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Biological Synthesis of Nanoparticles and Their Applications gives insight into the synthesis of nanoparticles utilizing the natural routes. It demonstrates various strategies for the synthesis of nanoparticles utilizing plants, microscopic organisms like bacteria, fungi, algae and so forth. It orchestrates interdisciplinary hypothesis, ideas, definitions, models and discoveries associated with complex ...
Biological Synthesis of Nanoparticles and Their Applications
Biological Synthesis of Nanoparticles and Their Applications gives insight into the synthesis of nanoparticles utilizing the natural routes. It demonstrates various strategies for the synthesis of nanoparticles utilizing plants, microscopic organisms like bacteria, fungi, algae and so forth. It orchestrates interdisciplinary hypothesis, ideas, definitions, models and discoveries associated with complex cell of the prokaryotes and eukaryotes. Highlights: Discusses biological approach towards the nanoparticle synthesis Describes the role of nanotechnology in the field of medicine and its medical devices Covers application and usage of the chemicals at the molecular level to act as catalysts and binding products for both organic and inorganic Chemical Reactions Reviews application in physics such as solar cells, photovoltaics and other usage Microorganisms can aggregate and detoxify substantial metals because of different reductase enzymes, which can diminish metal salts to metal nanoparticles. The readers after going through this book will have detailed account of mechanism of bio-synthesis of nanoparticles.
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241.450000 USD
Hardback
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The development of parallel synthesis and high-throughput characterization tools offer scientists a time-efficient and cost-effective solution for accelerating traditional synthesis processes and developing the structure-property relationships of multiple materials under variable conditions. Written by renowned contributors to the field, Combinatorial and High-Throughput Discovery and Optimization of Catalysts and Materials documents ...
Combinatorial and High-Throughput Discovery and Optimization of Catalysts and Materials
The development of parallel synthesis and high-throughput characterization tools offer scientists a time-efficient and cost-effective solution for accelerating traditional synthesis processes and developing the structure-property relationships of multiple materials under variable conditions. Written by renowned contributors to the field, Combinatorial and High-Throughput Discovery and Optimization of Catalysts and Materials documents the impact of combinatorial methods for inorganic, organic, polymeric, and biological materials applications over the last several years. This valuable reference describes techniques for the preparation, formulation, fabrication, optimization, performance testing, and evaluation of catalysts, polymeric materials arrays, sensing materials, fuel cell battery and memory materials, semiconductor nanoclusters, dielectrics, OLED arrays, additives, organic coatings, luminescent materials, and phosphors. The book introduces some of the latest features in the development of combinatorial and high throughput workflows, including new library designs, the scale-up of combinatorially discovered materials, and innovative methods of data storage, data mining and informatics. It also points to active research in the development of intelligent software for data mining including multiparameter modeling and visualization. As combinatorial materials science becomes increasingly applicable to a growing number of materials and problems, Combinatorial and High-Throughput Discovery and Optimization of Catalysts and Materials provides an essential portrait of the success, challenges, and opportunities in this field for the next generation of combinatorial chemists, material scientists, and industrial chemists and academics.
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78.700000 USD
Paperback / softback
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Presents the Therapeutic Potential for Caspase Inhibitors: Present and Future Caspases represent one of the most specific protease families described to date. These extremely important enzymes are crucial to the destruction of aberrant cells - the body's self-protection mechanism for warding off the growth of abnormal cells, many of which ...
Design of Caspase Inhibitors as Potential Clinical Agents
Presents the Therapeutic Potential for Caspase Inhibitors: Present and Future Caspases represent one of the most specific protease families described to date. These extremely important enzymes are crucial to the destruction of aberrant cells - the body's self-protection mechanism for warding off the growth of abnormal cells, many of which can promote cancer. Design of Caspase Inhibitors as Potential Clinical Agents introduces cutting-edge evidence regarding caspases' role in pro-inflammatory responses. New research now shows that the inhibition of caspase function is a critical component for the treatment of many diseases, including: Arthritic and neurological disorders Lung disease Hereditary fever syndromes Inflammatory bowel and skin diseases Sepsis Liver fibrosis Outlines Efforts to Develop Molecule Inhibitors for Caspase Activity Transformation Under the editorial guidance of authoritative inflammatory disease, small molecule discovery, and apoptosis researchers, the book organizes the wide array of caspase literature into one convenient resource. It also summarizes the relative difficulty of transitioning a caspase small molecule inhibitor from the lab to the clinic and suggests approaches to circumvent this difficulty. Taking a novel, yet core approach to disease treatment, this seminal work sets the stage to combat a slew of debilitating diseases through groundbreaking drug development.
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78.700000 USD
Paperback / softback
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This text offers in-depth perspectives on every aspect of protein structure identification, assessment, characterization, and utilization, for a clear understanding of the diversity of protein shapes, variations in protein function, and structure-based drug design. The authors cover numerous high-throughput technologies as well as computational methods to study protein structures and ...
Protein Structure: Determination, Analysis, and Applications for Drug Discovery
This text offers in-depth perspectives on every aspect of protein structure identification, assessment, characterization, and utilization, for a clear understanding of the diversity of protein shapes, variations in protein function, and structure-based drug design. The authors cover numerous high-throughput technologies as well as computational methods to study protein structures and residues. A valuable reference, this book reflects current trends in the effort to solve new structures arising from genome initiatives, details methods to detect and identify errors in the prediction of protein structural models, and outlines challenges in the conversion of routine processes into high-throughput platforms.
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78.700000 USD
Paperback / softback
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An exploration of new and emerging techniques, processes and applications in the behaviour, crystallization, and polymorphic transformations of fats and oils. It presents research and information on advanced analytical tools, computer modelling, molecular structures, mixing behaviour, and interactions with seeding materials and surfactants. The contributors spotlight developments in the food, ...
Crystallization Processes in Fats and Lipid Systems
An exploration of new and emerging techniques, processes and applications in the behaviour, crystallization, and polymorphic transformations of fats and oils. It presents research and information on advanced analytical tools, computer modelling, molecular structures, mixing behaviour, and interactions with seeding materials and surfactants. The contributors spotlight developments in the food, cosmetic and pharmaceutical industries, highlighting modern discoveries in polymorphic forms, self-assembled structures, and speciality fats and oils, emphasizing health, balanced nutrition, and functionality.
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78.700000 USD

Crystallization Processes in Fats and Lipid Systems

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This book continues the series Electroanalytical Chemistry: A Series of Advances, designed to provide authoritative reviews on recent developments and applications of well-established techniques in the field of electroanalytical chemistry. Electroanalytical techniques are used in a wide range of studies, including electro-organic synthesis, fuel cell studies, and radical ion formation. ...
Electroanalytical Chemistry: A Series of Advances: Volume 26
This book continues the series Electroanalytical Chemistry: A Series of Advances, designed to provide authoritative reviews on recent developments and applications of well-established techniques in the field of electroanalytical chemistry. Electroanalytical techniques are used in a wide range of studies, including electro-organic synthesis, fuel cell studies, and radical ion formation. Each chapter in this volume provides comprehensive coverage of a subject area, including detailed descriptions of techniques, derivations of fundamental equations, and discussions of important related articles. The primary topics include: Nanoscale scanning electrochemical microscopy Electrochemical applications of scanning ion conductance microscopy Electrode surface modification using diazonium salts Each volume in the series provides the necessary background and a starting point for graduate students undertaking related research projects. They are also of particular interest to practicing analytical chemists concerned with learning and applying electroanalytical techniques and the fundamental theoretical principles upon which these techniques are based.
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USD
Paperback / softback
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Crystallography is one of the most multidisciplinary sciences, with roots in fields as varied as mathematics, physics, chemistry, biology, materials science, computation and earth and planetary science. The structural knowledge gained from crystallography has been instrumental in acquiring new levels of understanding in numerous scientific areas. Perspectives in Crystallography provides ...
Perspectives in Crystallography
Crystallography is one of the most multidisciplinary sciences, with roots in fields as varied as mathematics, physics, chemistry, biology, materials science, computation and earth and planetary science. The structural knowledge gained from crystallography has been instrumental in acquiring new levels of understanding in numerous scientific areas. Perspectives in Crystallography provides an overview of the current state of the field, reviews its historical origins and explains how crystallography contributes to the sustainability of life. This book resonates with the recent United Nations and UNESCO International Year of Crystallography, a celebration of its achievements and importance, undertaken with the International Union of Crystallography. The author of this book is the editor in chief of Crystallography Reviews, where some of the contents have been previously published. Here, subjects of interest to specialists and non-specialists have been brought together in a single source. The book opens with a description of the ways to explain crystallography to diverse general audiences. It also addresses various topics in crystallography, including: The evolution and importance of synchrotron radiation to crystallography The structural chemistry and biology of colouration in marine crustacea Predicting protonation states of proteins versus crystallographic experimentation The book then offers a projection of crystal structure analysis in the next 100 years and concludes by emphasizing the societal impacts of crystallography that allow for sustainability of life. Perspectives in Crystallography offers a threefold look into the past, present and long-term development and relevance of crystal structure analysis. It is concerned not only with the state of the field, but with its role in the perpetuation of life on earth. As such, it is a reference of vital interest to a bro
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78.700000 USD
Paperback / softback
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Taking an interdisciplinary approach that emphasizes the adaptability of immunochemical and related bioanalytical methods to a variety of matrices, Immunoassay and Other Bioanalytical Techniques describes the strength and the versatility of these methods in a wide range of environmental and biological measurement applications. With contributions from leading authors drawn from ...
Immunoassay and Other Bioanalytical Techniques
Taking an interdisciplinary approach that emphasizes the adaptability of immunochemical and related bioanalytical methods to a variety of matrices, Immunoassay and Other Bioanalytical Techniques describes the strength and the versatility of these methods in a wide range of environmental and biological measurement applications. With contributions from leading authors drawn from varied disciplines in academia, industry, and government institutions, the book discusses the evolution of the technology and explores the wide spectrum of chemicalimmuno methods available, including multiplexed immunoassays. It presents standard and innovative applications of immunochemical and related methods, such as microarrays and sensors, examines quality assurance guidelines, and offers insight into recently developed products and procedures. Meeting the continuing and pressing need for economical analytical methods that can detect trace levels of hazardous compounds in complex environmental and biological media, this text reviews breakthrough research, including the impact of nanotechnology. It describes the strength and versatility of immunochemical and related bioanalytical methods while highlighting other areas of applied bioanalytical methods. The book provides both a basic understanding of the field and an update on important technological advances such as new platforms and detection systems. It demonstrates how significant time and cost savings can be achieved for studies requiring repetitive analysis or having high sample loads.
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78.700000 USD
Paperback / softback
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Computational Methods for Complex Liquid-Fluid Interfaces highlights key computational challenges involved in the two-way coupling of complex liquid-fluid interfaces. The book covers a variety of cutting-edge experimental and computational techniques ranging from macro- to meso- and microscale approaches (including pivotal applications). As examples, the text: defines the most important interfacial ...
Computational Methods for Complex Liquid-Fluid Interfaces
Computational Methods for Complex Liquid-Fluid Interfaces highlights key computational challenges involved in the two-way coupling of complex liquid-fluid interfaces. The book covers a variety of cutting-edge experimental and computational techniques ranging from macro- to meso- and microscale approaches (including pivotal applications). As examples, the text: defines the most important interfacial quantities and their experimental investigations, providing theoretical background and detailed solutions, describes vital techniques used in interfacial flow problems, such as modern meshless numerical methods and conventional computational fluid dynamics methods, and discusses the technicalities of correctly using the computational methods developed for interfacial flows, as well as the simulation of interesting interfacial flow physics. Edited and authored by leading scientists and researchers, Computational Methods for Complex Liquid-Fluid Interfaces offers an authoritative and state-of-the-art overview of computational methodologies and simulation techniques for the quantification of interfacial quantities.
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78.700000 USD

Computational Methods for Complex Liquid-Fluid Interfaces

Paperback / softback
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The unprecedented potential of nanotechnology for early detection, diagnosis, and personalized treatment of diseases has found application in every biomedical imaging modality. However, with the increasing concern about the ethical and toxicity issues associated with some nanoplatforms, biomedical researchers are in pursuit of safer, more precise, and effective ways to ...
Nanomedicine: A Soft Matter Perspective
The unprecedented potential of nanotechnology for early detection, diagnosis, and personalized treatment of diseases has found application in every biomedical imaging modality. However, with the increasing concern about the ethical and toxicity issues associated with some nanoplatforms, biomedical researchers are in pursuit of safer, more precise, and effective ways to practice nanomedicine. Designed and written to be accessible to anyone, with or without previous knowledge of nanotechnology, Nanomedicine: A Soft Matter Perspective takes a balanced look at potential pitfalls and challenges faced by the field and how they can be translated into nonomedicine technologies. A multidisciplinary and fast-evolving research area, nanomedicine presents new clinically relevant promises grounded in the disciplines of molecular biology, genomics, chemistry, and nanotechnology. Nanoparticle-based theranostic approaches have emerged as an interdisciplinary area, which shows promise to understand the components, processes, dynamics, and therapies of a disease at a molecular level. This book discusses some of the unique opportunities presented by biomaterials at the nanoscale. The book provides a broad introduction to the areas of nanomedicinal application with an emphasis on imaging and therapeutics. It covers soft nanoscopic objects with prerequisite features for different imaging modalities with a potential for image-guided drug delivery. The book also offers a general introduction to the various drug delivery systems and their opportunities from chemistry, materials, biology, and nanomedical standpoints. The chapters provide a comprehensive introduction to the field and the subfield, with a deeper discussion on the individual modalities for molecular imaging and their present status of clinical translation.
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78.700000 USD
Paperback / softback
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A Century of Separation Science presents an extensive overview of the critical developments in separation science since 1900, covering recent advances in chromatography, electrophoresis, field-flow fractionation, countercurrent chromatography, and supercritical fluid chromatography for high-speed and high-throughput analysis.
A Century of Separation Science
A Century of Separation Science presents an extensive overview of the critical developments in separation science since 1900, covering recent advances in chromatography, electrophoresis, field-flow fractionation, countercurrent chromatography, and supercritical fluid chromatography for high-speed and high-throughput analysis.
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78.700000 USD

A Century of Separation Science

Paperback / softback
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The vast and exciting Brazilian flora biodiversity is still underexplored. Several research groups are devoted to the study of the chemical structure richness found in the different Biomes. This volume presents a comprehensive account of the research collated on natural products produced from Brazilian medicinal plants and focuses on various ...
Brazilian Medicinal Plants
The vast and exciting Brazilian flora biodiversity is still underexplored. Several research groups are devoted to the study of the chemical structure richness found in the different Biomes. This volume presents a comprehensive account of the research collated on natural products produced from Brazilian medicinal plants and focuses on various aspects of the field. The authors describe the key natural products and their extracts with emphasis upon sources, an appreciation of these complex molecules and applications in science. Many of the extracts are today associated with important drugs, nutrition products, beverages, perfumes, cosmetics and pigments, and these are highlighted. Key Features: Presents Brazilian biodiversity: its flora, its people, and its research Describes the emergence of natural products research in Brazil Emphasizes the increasing global interests in botanical drugs Aids the international natural product communities to better understand the herbal resources in Brazil Discusses Brazilian legislation to work with native plants
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188.950000 USD
Hardback
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This comprehensive text covers the research and development trends in the growing field of aromatic C-H dehydrogenative coupling reactions, leading to different types of heterocycles. The author provides answers to how these coupling reactions occur, what kinds of heterocycles are synthesized, and what their advantages are. The palladium-, rhodium-, iridium-, ...
Aromatic C(sp2) H Dehydrogenative Coupling Reactions: Heterocycles Synthesis
This comprehensive text covers the research and development trends in the growing field of aromatic C-H dehydrogenative coupling reactions, leading to different types of heterocycles. The author provides answers to how these coupling reactions occur, what kinds of heterocycles are synthesized, and what their advantages are. The palladium-, rhodium-, iridium-, copper-, cobalt-, ruthenium-, and ferric-catalyzed aromatic C(sp2)-H dehydrogenative cross-coupling reactions are described in detail. A useful reference source for researchers and graduates in the field of heterocyclic chemistry and transition-metal-catalyzed dehydrogenative coupling reactions. Features: Comprehensive volume on the synthesis of benzo-heterocycles via aromatic C(sp2)-H bond activation. Heterocycles are of paramount importance to medicinal chemistry and drug discovery. Provides a comprehensive literature survey on the construction of heterocycles. Reaction procedures and mechanistic explanations are included, which will appeal to those in fine chemicals and pharmaceutical companies.
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210.000000 USD
Hardback
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Scientific and Commercial Information for More Than 1,000 Polymers Polymers: A Property Database, Second Edition offers a central and reliable source for scientific and commercial information on more than 1,000 polymers. Revised and updated throughout, this edition features 25% new material, including 50 entirely new entries that reflect advances in ...
Polymers: A Property Database, Second Edition
Scientific and Commercial Information for More Than 1,000 Polymers Polymers: A Property Database, Second Edition offers a central and reliable source for scientific and commercial information on more than 1,000 polymers. Revised and updated throughout, this edition features 25% new material, including 50 entirely new entries that reflect advances in areas such as conducting polymers, hydrogels, nano-polymers, and biomaterials. The second edition also comes with unlimited access to a complete, fully searchable Web version of the reference. Powerful retrieval software allows users to customize their searches and refine results. Each entry includes trade names, properties, manufacturing processes, commercial applications, supplier details, references, and links to constituent monomers. Buy the latest print edition and gain access to a complete, fully searchable Web version of the reference, enhanced with powerful retrieval software that allows you to customize searches and refine results. Unlimited access to the Online Version for the lifetime of the Second Edition Revised, Updated, and Expanded with 25% New Material Includes 50 entirely new entries reflecting the latest polymer advances Special Introductory Price! Buy today and SAVE! Purchase the NEW Edition in Print AND Online -For One Price!
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262.500000 USD
Paperback / softback
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The isolation and structural characterization of substances present at very low concentrations, as is necessary to satisfy regulatory requirements for pharmaceutical drug degradants and impurities, can present scientific challenges. The coupling of HPLC with NMR spectroscopy has been at the forefront of cutting-edge technologies to address these issues. LC-NMR: Expanding ...
LC-NMR: Expanding the Limits of Structure Elucidation
The isolation and structural characterization of substances present at very low concentrations, as is necessary to satisfy regulatory requirements for pharmaceutical drug degradants and impurities, can present scientific challenges. The coupling of HPLC with NMR spectroscopy has been at the forefront of cutting-edge technologies to address these issues. LC-NMR: Expanding the Limits of Structure Elucidation presents a comprehensive overview of key concepts in HPLC and NMR that are required to achieve definitive structure elucidation with very low levels of analytes. Because skill sets from both of these highly established disciplines are involved in LC-NMR, the author provides introductory background to facilitate readers' proficiency in both areas, including an entire chapter on NMR theory. This book provides guidance in setting up LC-NMR systems, discussion of LC methods that are compatible with NMR, and an update on recent hardware and software advances for system performance, such as improvements in magnet design, probe technology, and solvent suppression techniques that enable unprecedented mass sensitivity in NMR. It also describes numerous NMR collection strategies, including continuous flow, stop flow, solid phase extraction (SPE), loop collection, and capillary electrophoresis. In addition, the author presents an overview of NMR experiments and techniques used in structure elucidation. The text focuses on current developments in chromatographic-NMR integration, with particular emphasis on utility in the pharmaceutical industry. Applications include trace analysis, analysis of mixtures, and detection of degradation products, impurities, metabolites, peptides, and more. The text discusses novel uses and emerging technologies that challenge detection limits as well future directions for this important technique. This book is a practical primary resource for NMR structure determination-including theory and application-that guid
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78.700000 USD
Paperback / softback
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There are essentially two theories of solutions that can be considered exact: the McMillan-Mayer theory and Fluctuation Solution Theory (FST). The first is mostly limited to solutes at low concentrations, while FST has no such issue. It is an exact theory that can be applied to any stable solution regardless ...
Fluctuation Theory of Solutions: Applications in Chemistry, Chemical Engineering, and Biophysics
There are essentially two theories of solutions that can be considered exact: the McMillan-Mayer theory and Fluctuation Solution Theory (FST). The first is mostly limited to solutes at low concentrations, while FST has no such issue. It is an exact theory that can be applied to any stable solution regardless of the number of components and their concentrations, and the types of molecules and their sizes. Fluctuation Theory of Solutions: Applications in Chemistry, Chemical Engineering, and Biophysics outlines the general concepts and theoretical basis of FST and provides a range of applications described by experts in chemistry, chemical engineering, and biophysics. The book, which begins with a historical perspective and an introductory chapter, includes a basic derivation for more casual readers. It is then devoted to providing new and very recent applications of FST. The first application chapters focus on simple model, binary, and ternary systems, using FST to explain their thermodynamic properties and the concept of preferential solvation. Later chapters illustrate the use of FST to develop more accurate potential functions for simulation, describe new approaches to elucidate microheterogeneities in solutions, and present an overview of solvation in new and model systems, including those under critical conditions. Expert contributors also discuss the use of FST to model solute solubility in a variety of systems. The final chapters present a series of biological applications that illustrate the use of FST to study cosolvent effects on proteins and their implications for protein folding. With the application of FST to study biological systems now well established, and given the continuing developments in computer hardware and software increasing the range of potential applications, FST provides a rigorous and useful approach for understanding a wide array of solution properties. This book outlines those approaches, and their advantages, ac
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78.700000 USD
Paperback / softback
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A complex disease involves many etiological and risk factors operating at multiple levels-molecular, cellular, organismal, and environmental. The incidence of such diseases as cancer, obesity, and diabetes are increasing in occurrence, urging us to think fundamentally and use a broader perspective to identify their connection and revolutionize treatments. The understanding ...
Analysis of Complex Diseases: A Mathematical Perspective
A complex disease involves many etiological and risk factors operating at multiple levels-molecular, cellular, organismal, and environmental. The incidence of such diseases as cancer, obesity, and diabetes are increasing in occurrence, urging us to think fundamentally and use a broader perspective to identify their connection and revolutionize treatments. The understanding of biological data derived from studying diseases can be enhanced by theories and mathematical models, which clarify the big picture and help to reveal the overarching mechanisms that govern complex biological phenomena. Focusing on diseases related to cellular energy metabolism, such as cancer and diabetes, Analysis of Complex Diseases: A Mathematical Perspective presents a holistic approach for illuminating the molecular mechanisms of these diseases and the evolutionary underpinning of their simultaneous epidemics. Using mathematics to identify patterns of deviation from normality, or the healthy state-spanning multiple levels from molecules to the organism-the author identifies a range of dynamical behaviors that correspond to either cellular physiology or pathology. He uses the information from multiple levels in order to develop a unified theory, which includes the discovery that certain diseases may stem from well-evolved, useful mechanisms activated in the wrong context. This book is divided into three parts. Part I focuses on the organismal level to describe normal physiology and how the body as a whole meets its functional requirements. Part II addresses the subcellular, molecular level to elucidate the organizing principles of cellular biomolecules to meet the demands of the organism. Part III examines complex diseases by combining information from the organismal level and the molecular level, offering a paradigm that can be extended to the study of other categories of diseases.
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78.700000 USD
Paperback / softback
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