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This book introducing all researchers and students who are interested in pursuing their research in the field of application of carbon dots in health care especially as a theranostic agent. It focuses on the fundamental understanding along with the applications of this unique fluorescent nanobiomachine, the Carbon Dot. The book ...
Carbon Dots As Theranostic Agents
This book introducing all researchers and students who are interested in pursuing their research in the field of application of carbon dots in health care especially as a theranostic agent. It focuses on the fundamental understanding along with the applications of this unique fluorescent nanobiomachine, the Carbon Dot. The book begins with the explanation that carbon dots fall between the usual daily macro or bulk physics and the quantum mechanics and covers their unique properties like quantum mechanics and quantum confinement. It then encompasses the domain of various physical, chemical and biological methods that efficiently synthesizes the carbon dots and their desired properties. The basic characterization techniques used for carbon dots is also covered in this book. Conjugation of carbon dots with different moieties is another aspect that enhances its applications, hence this is highlighted too. The final attributes of this book is that how to maneuver the carbon dots for their use in targeted drug delivery with emphasis on cancer and neurodegenerative disease as well as cellular imaging and diagnostics. One of the unique features of this book is that it has looked into the use of carbon dots to act as a nanofertilizer, as a drug/antibiotic delivery vehicle to diseased plants through foliar application.
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USD

Carbon Dots As Theranostic Agents

by Ashmi Mewada, Madhuri Sharon
Hardback
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This book discusses various fundamental aspects of polysaccharide based nano-biocarrier drug delivery systems and its application in the delivery of small molecules, proteins, peptides, oligonucleotides and genes. It also discusses advances in drug delivery systems in treatment of cancer, cardiovascular, pulmonary, and infectious diseases.
Polysaccharide based Nano-Biocarrier in Drug Delivery
This book discusses various fundamental aspects of polysaccharide based nano-biocarrier drug delivery systems and its application in the delivery of small molecules, proteins, peptides, oligonucleotides and genes. It also discusses advances in drug delivery systems in treatment of cancer, cardiovascular, pulmonary, and infectious diseases.
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264.47 USD

Polysaccharide based Nano-Biocarrier in Drug Delivery

Hardback
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The first review describes examples of very promising compounds discovered from plants acquired from Africa, Southeast Asia, the Americas, and the Caribbean region with potential anticancer activity. These include plant secondary metabolites of the diphyllin lignan, penta[b]benzofuran, triterpenoid, and tropane alkaloid types. The second review presents 40 more erythrinan alkaloids, ...
Progress in the Chemistry of Organic Natural Products 107
The first review describes examples of very promising compounds discovered from plants acquired from Africa, Southeast Asia, the Americas, and the Caribbean region with potential anticancer activity. These include plant secondary metabolites of the diphyllin lignan, penta[b]benzofuran, triterpenoid, and tropane alkaloid types. The second review presents 40 more erythrinan alkaloids, which were either new or were missed out in the last major reviews, bringing to a total of 154 known erythrinan alkaloids known to date. The reported pharmacological activities of the new and known alkaloids showed a greater bias towards central nervous system and related activities. Other prominent activities reported were antifeedant or insecticidal, cytotoxicity/anti-tumor/anti-cancer/estrogenic, antiprotozoal, antiinflammatory, antioxidant, antifungal and antiviral activities.
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314.990000 USD

Progress in the Chemistry of Organic Natural Products 107

Hardback
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This first monograph in the new AAPS book series concisely reviews important aspects of powder and particle systems and the critical quality attributes that should be used as a guide to future developments intended to maximize the control of product quality and performance. Drs. Hickey and Giovagnoli have written an ...
Pharmaceutical Powder and Particles
This first monograph in the new AAPS book series concisely reviews important aspects of powder and particle systems and the critical quality attributes that should be used as a guide to future developments intended to maximize the control of product quality and performance. Drs. Hickey and Giovagnoli have written an essential primer for any scientists involved in powder or particle research and manufacturing. It is appropriate for those just entering the field or as a rapid reference for the experienced pharmaceutical scientist. The authors have both academic and industrial experience and the coverage includes solid state chemistry; crystallization; physical processes; particle size and distribution;particle interaction;manufacturing processes;quality by design;and a general discussion of the industry. Pharmaceutical Powder and Particles is intended to concisely review important aspects of powder and particle systems and the critical quality attributes that should be used as a guide to future developments intended to maximize the control of product quality and performance.
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167.990000 USD

Pharmaceutical Powder and Particles

by Stefano Giovagnoli, Anthony J Hickey
Hardback
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This book addresses a range of synthesis and characterization techniques that are critical for tailoring and broadening the various aspects of polymer gels, as well as the numerous advantages that polymer gel-based materials offer. It presents a comprehensive collection of chapters on the recent advances and developments in the science ...
Polymer Gels: Synthesis and Characterization
This book addresses a range of synthesis and characterization techniques that are critical for tailoring and broadening the various aspects of polymer gels, as well as the numerous advantages that polymer gel-based materials offer. It presents a comprehensive collection of chapters on the recent advances and developments in the science and fundamentals of both synthetic and natural polymer-based gels. Topics covered include: synthesis and structure of physically/chemically cross-linked polymer-gels/polymeric nanogels; gel formation through non-covalent cross-linking; molecular design and characterization; polysaccharide-based polymer gels: synthesis, characterization, and properties; modified polysaccharide gels: silica-based polymeric gels as platforms for the delivery of pharmaceuticals; gel-based approaches in genomic and proteomic sciences; emulgels in drug delivery; and organogels. The book provides a cutting-edge resource for researchers and scientists working in various fields involving polymers, biomaterials, bio-nanotechnology and functional materials.
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167.990000 USD

Polymer Gels: Synthesis and Characterization

Hardback
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Among the most anticipated and discussed segments of the pharmaceutical market, biosimilars, are finally beginning to exert a greater impact on practice. To meet the growing need for information, ASHP has published Biosimilars and Biologics. This authoritative, evidence-based resource provides an in-depth perspective on all areas related to these innovative ...
Biosimilars and Biologics: Implementation and Monitoring in a Healthcare Setting
Among the most anticipated and discussed segments of the pharmaceutical market, biosimilars, are finally beginning to exert a greater impact on practice. To meet the growing need for information, ASHP has published Biosimilars and Biologics. This authoritative, evidence-based resource provides an in-depth perspective on all areas related to these innovative drugs, including: * Legislative/regulatory issues, including the biosimilars act and anticipated FDA guidelines * The safety, efficacy, and interchangeability of biologics * The science and analytical chemistry associated with the manufacture of biologics * Needed pharmacovigilance and adverse effect reporting systems * Formulary management
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218.40 USD

Biosimilars and Biologics: Implementation and Monitoring in a Healthcare Setting

by Steven Lucio
Paperback / softback
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3D printing is forecast to revolutionise the pharmaceutical sector, changing the face of medicine development, manufacture and use. Potential applications range from pre-clinical drug development and dosage form design through to the fabrication of functionalised implants and regenerative medicine. Within clinical pharmacy practice, printing technologies may finally lead to the ...
3D Printing of Pharmaceuticals
3D printing is forecast to revolutionise the pharmaceutical sector, changing the face of medicine development, manufacture and use. Potential applications range from pre-clinical drug development and dosage form design through to the fabrication of functionalised implants and regenerative medicine. Within clinical pharmacy practice, printing technologies may finally lead to the concept of personalised medicines becoming a reality. This volume aims to be the definitive resource for anyone thinking of developing or using 3D printing technologies in the pharmaceutical sector, with a strong focus on the translation of printing technologies to a clinical setting. This text brings together leading experts to provide extensive information on an array of 3D printing techniques, reviewing the current printing technologies in the pharmaceutical manufacturing supply chain, in particular, highlighting the state-of-the-art applications in medicine and discussing modern drug product manufacture from a regulatory perspective. This book is a highly valuable resource for a range of demographics, including academic researchers and the pharmaceutical industry, providing a comprehensive inventory detailing the current and future applications of 3D printing in pharmaceuticals. Abdul W. Basit is Professor of Pharmaceutics at the UCL School of Pharmacy, University College London. Abdul's research sits at the interface between pharmaceutical science and gastroenterology, forging links between basic science and clinical outcomes. He leads a large and multidisciplinary research group, and the goal of his work is to further the understanding of gastrointestinal physiology by fundamental research. So far, this knowledge has been translated into the design of new technologies and improved disease treatments, many of which are currently in late-stage clinical trials. He has published over 350 papers, book chapters and abstracts and delivered more than 250 invited research presentations. Abdul is also a serial entrepreneur and has filed 25 patents and founded 3 pharmaceutical companies (Kuecept, Intract Pharma, FabRx). Abdul is a frequent speaker at international conferences, serves as a consultant to many pharmaceutical companies and is on the advisory boards of scientific journals, healthcare organisations and charitable bodies. He is the European Editor of the International Journal of Pharmaceutics. Abdul was the recipient of the Young Investigator Award in Pharmaceutics and Pharmaceutical Technology from the American Association of Pharmaceutical Scientists (AAPS) and is the only non-North American scientist to receive this award. He was also the recipient of the Academy of Pharmaceutical Sciences (APS) award. Simon Gaisford holds a Chair in Pharmaceutics and is Head of the Department of Pharmaceutics at the UCL School of Pharmacy, University College London. He has published 110 papers, 8 book chapters and 4 authored books. His research is focused on novel technologies for manufacturing medicines, particularly using ink-jet printing and 3D printing, and he is an expert in the physico-chemical characterisation of compounds and formulations with thermal methods and calorimetry.
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178.490000 USD

3D Printing of Pharmaceuticals

Hardback
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Authored by leading experts from academia, users and manufacturers, this book provides an authoritative account of the science and technology involved in multiparticulate drug delivery systems which offer superior clinical and technical advantages over many other specialized approaches in drug delivery. The book will cover market trends, potential benefits and ...
Multiparticulate Drug Delivery: Formulation, Processing and Manufacturing
Authored by leading experts from academia, users and manufacturers, this book provides an authoritative account of the science and technology involved in multiparticulate drug delivery systems which offer superior clinical and technical advantages over many other specialized approaches in drug delivery. The book will cover market trends, potential benefits and formulation challenges for various types of multiparticulate systems. Drug solubility, dose, chemistry and therapeutic indications as well as excipient suitability coupled with manufacturing methods will be fully covered. Key approaches for taste-masking, delayed release and extended release of multiparticulates systems are of significant interest, especially their in-vivo and in-vitro performance. In addition, the principles of scale-up, QbD, and regulatory aspects of common materials used in this technology will be explained, as well as recent advances in materials and equipment enabling robust, flexible and cost-effective manufacture. Case studies illustrating best practices will also make the book a valuable resource to pharmaceutical scientists in industry and academia.
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230.990000 USD

Multiparticulate Drug Delivery: Formulation, Processing and Manufacturing

Paperback / softback
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Medicines, Ethics and Practice: The professional guide for pharmacists is the Royal Pharmaceutical Society's established professional guide for pharmacists. This 42nd edition is a revised practical resource which helps pharmacists practice confidently and professionally. It embeds professionalism at the heart of decision-making processes and provides essential information, supporting the pharmacist ...
Medicines, Ethics and Practice 2018: The professional guide for pharmacists
Medicines, Ethics and Practice: The professional guide for pharmacists is the Royal Pharmaceutical Society's established professional guide for pharmacists. This 42nd edition is a revised practical resource which helps pharmacists practice confidently and professionally. It embeds professionalism at the heart of decision-making processes and provides essential information, supporting the pharmacist in their day-to-day practice.
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93.85 USD

Medicines, Ethics and Practice 2018: The professional guide for pharmacists

by Royal Pharmaceutical Society
Paperback / softback
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In this volume, the authors discuss the many significant challenges currently faced in biotechnology dosage form development, providing guidance, shared experience and thoughtful reflection on how best to address these potential concerns. As the field of therapeutic recombinant therapeutic proteins enters its fourth decade and the market for biopharmaceuticals becomes ...
Challenges in Protein Product Development
In this volume, the authors discuss the many significant challenges currently faced in biotechnology dosage form development, providing guidance, shared experience and thoughtful reflection on how best to address these potential concerns. As the field of therapeutic recombinant therapeutic proteins enters its fourth decade and the market for biopharmaceuticals becomes increasingly competitive, companies are increasingly dedicating resources to develop innovative biopharmaceuticals to address unmet medical needs. Often, the pharmaceutical development scientist is encountering challenging pharmaceutical properties of a given protein or by the demands placed on the product by stability, manufacturing and preclinical or clinical expectations, as well as the evolving regulatory expectations and landscape. Further, there have been new findings that require close assessment, as for example those related to excipient quality, processing, viscosity and device compatibility and administration, solubility and opalescence and container-closure selection. The literature varies widely in its discussion of these critical elements and consensus does not exist. This topic is receiving a great deal of attention within the biotechnology industry as well as with academic researchers and regulatory agencies globally. Therefore, this book is of interest for business leaders, researchers, formulation and process development scientists, analytical scientists, QA and QC officers, regulatory staff, manufacturing leaders and regulators active in the pharmaceutical and biotech industry, and expert reviewers in regulatory agencies.
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293.990000 USD

Challenges in Protein Product Development

Hardback
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The book HSP70 in Human Diseases and Disorders provides the most comprehensive review on contemporary knowledge on the role of HSP70 family - one of the most studied HSP - in human diseases and disorders. Using an integrative approach to expand our current understanding of HSP70 functions, the contributors provide ...
HSP70 in Human Diseases and Disorders
The book HSP70 in Human Diseases and Disorders provides the most comprehensive review on contemporary knowledge on the role of HSP70 family - one of the most studied HSP - in human diseases and disorders. Using an integrative approach to expand our current understanding of HSP70 functions, the contributors provide a synopsis of novel mechanisms by which HSP70 is involved in the regulation of human diseases and disorders. Key basic and clinical research laboratories from major universities and academic medical hospitals around the world contribute chapters that review present research activity and importantly project the field into the future. The book is a must read for medical students and residents, clinical and basic science researchers, postdoctoral fellows and graduate students in the fields of Medicine, Physiology, Clinical Trials, Biotechnology, Molecular Medicine and Pathology.
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188.990000 USD

HSP70 in Human Diseases and Disorders

Hardback
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The objective of this volume is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist's approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound's physiochemical properties, ...
Formulating Poorly Water Soluble Drugs
The objective of this volume is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist's approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound's physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at minimum a working knowledge of each of the abovementioned facets and detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop
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293.990000 USD

Formulating Poorly Water Soluble Drugs

Paperback / softback
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While systems biology and pharmacodynamics have evolved in parallel, there are significant interrelationships that can enhance drug discovery and enable optimized therapy for each patient. Systems pharmacology is the relatively new discipline that is the interface between these two methods. This book is the first to cover the expertise from ...
Systems Pharmacology and Pharmacodynamics
While systems biology and pharmacodynamics have evolved in parallel, there are significant interrelationships that can enhance drug discovery and enable optimized therapy for each patient. Systems pharmacology is the relatively new discipline that is the interface between these two methods. This book is the first to cover the expertise from systems biology and pharmacodynamics researchers, describing how systems pharmacology may be developed and refined further to show practical applications in drug development. There is a growing awareness that pharmaceutical companies should reduce the high attrition in the pipeline due to insufficient efficacy or toxicity found in proof-of-concept and/or Phase II studies. Systems Pharmacology and Pharmacodynamics discusses the framework for integrating information obtained from understanding physiological/pathological pathways (normal body function system vs. perturbed system due to disease) and pharmacological targets in order to predict clinical efficacy and adverse events through iterations between mathematical modeling and experimentation.
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262.490000 USD

Systems Pharmacology and Pharmacodynamics

Paperback / softback
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SAFETY FIRST! Davis's Drug Guide for Nurses(R) Canadian Version, Sixteenth Edition delivers all of the information you need to administer medications safely across the lifespan--well-organized monographs for hundreds of generic and thousands of trade-name drugs. BONUS! FREE DIGITAL ACCESS www.DrugGuide.com Redeem the access code inside to unlock your one-year, free ...
Davis's Drug Guide for Nurses Canadian Version
SAFETY FIRST! Davis's Drug Guide for Nurses(R) Canadian Version, Sixteenth Edition delivers all of the information you need to administer medications safely across the lifespan--well-organized monographs for hundreds of generic and thousands of trade-name drugs. BONUS! FREE DIGITAL ACCESS www.DrugGuide.com Redeem the access code inside to unlock your one-year, free subscription to Davis's Drug Guide Online, powered by Unbound Medicine. It's accessible from your desktop, laptop, or any mobile device with a web browser 5,000-drug database and appendices Cross-referencing of drugs FDA drug news LIFE-SAVING GUIDANCE ... AT A GLANCE Canadian-specific content Monographs on drugs approved for use in Canada that are not FDA-approved for use in the US Additional Canadian trade names for many US-approved generic drugs, identified by a maple leaf icon A summary of the similarities and differences between pharmaceutical practices in the US and Canada Special contributions by Holly G. Mansell, BSP, PharmD, Assistant Professor of Pharmacy, College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, SK, Canada Canadian Advisory Board of clinicians, educators, and students Red tab for high alert medications, plus in-depth high alert and patient safety coverage Red, capitalized letters for life-threatening side effects NEW! REP heading for use of drugs in males and females of reproductive age Drug-drug, drug-food, drug-natural product interactions Pedi, Geri, OB, and Lactation cautions IV administration subheads REMS (Risk Evaluation and Mitigation Strategies) icon Pharmacogenomic content and icon Much more! LEARNING, CARE-PLANNING, AND PATIENT EDUCATION TOOLS Online at DavisPlus Pronunciation library for 1,200+ drug names Preventing med errors and psychotropic drug tutorials, each with a self-test Calculators for body mass index (BMI), metric conversions, IV drip rates, dosage/kg, and Fahrenheit/Celsius Interactive case studies, brief, real-life scenarios that are followed by a series of question Video clips illustrating the safe administration of medications Animations demonstrating the administration and absorption of oral drugs Reviews for Davis's Drug Guide for Nurses, 15th Edition Invaluable. This... resource has been invaluable for my clinicals and pharm class. --CJ Bob Perfect for a nursing student. I feel that I didn't need my pharmacology book, and could have just used this. It's organized and comprehensive, and for each drug has nursing implications with assessments, potential nursing diagnoses, teaching, and evaluations. --Amazon Reviewer This is your book. If you want to know about drugs, this is your book. Very thorough and helpful with my nursing classes. --Michael Grewing. Use this every day! The most helpful book ever created for Pharmacology! I use this every single day! --C. Kelly A Must-Have. An absolute must have. Great Book.--Rocco DeMario Hands down the best drug guide. I am very pleased with this drug guide. I am in nursing school and this is the best drug guide hands down. I used other brands and I feel this is more organized and better to understand. --Carolina Cruz
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52.450000 USD

Davis's Drug Guide for Nurses Canadian Version

by April Hazard Vallerand
Paperback / softback
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This book provides information on best practices and new thinking regarding the validation of alternative methods for toxicity testing. It covers the validation of experimental and computational methods and integrated approaches to testing and assessment. Validation strategies are discussed for methods employing the latest technologies such as tissue-on-a-chip systems, stem ...
Validation of Alternative Methods for Toxicity Testing
This book provides information on best practices and new thinking regarding the validation of alternative methods for toxicity testing. It covers the validation of experimental and computational methods and integrated approaches to testing and assessment. Validation strategies are discussed for methods employing the latest technologies such as tissue-on-a-chip systems, stem cells and transcriptomics, and for methods derived from pathway-based concepts in toxicology. Validation of Alternative Methods for Toxicity Testing is divided into two sections, in the first, practical insights are given on the state-of-the-art and on approaches that have resulted in successfully validated and accepted alternative methods. The second section focuses on the evolution of validation principles and practice that are necessary to ensure fit-for-purpose validation that has the greatest impact on international regulatory acceptance of alternative methods. In this context validation needs to keep pace with the considerable scientific advancements being made in toxicology, the availability of sophisticated tools and techniques that can be applied in a variety of ways, and the increasing societal and regulatory demands for better safety assessment. This book will be a useful resource for scientists in the field of toxicology, both from industry and academia, developing new test methods, strategies or techniques, as well as Governmental and regulatory authorities interested in understanding the principles and practicalities of validation of alternative methods for toxicity testing.
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230.990000 USD

Validation of Alternative Methods for Toxicity Testing

Paperback / softback
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This consolidated reference book addresses the various aspects of nano biomaterials used in ophthalmic drug delivery, including their characterization, interactions with ophthalmic system and applications in treatments of the ophthalmic diseases and disorders. In the last decade, a significant growth in polymer sciences, nanotechnology and biotechnology has resulted in the ...
Nano-Biomaterials For Ophthalmic Drug Delivery
This consolidated reference book addresses the various aspects of nano biomaterials used in ophthalmic drug delivery, including their characterization, interactions with ophthalmic system and applications in treatments of the ophthalmic diseases and disorders. In the last decade, a significant growth in polymer sciences, nanotechnology and biotechnology has resulted in the development of new nano- and bioengineered nano-bio-materials. These are extensively explored as drug delivery carriers as well as for implantable devices and scaffolds. At the interface between nanomaterials and biological systems, the organic and synthetic worlds merge into a new science concerned with the safe use of nanotechnology and nano- material design for biological applications. For this field to evolve, there is a need to understand the dynamic forces and molecular components that shape these interactions. While it is impossible to describe with certainty all the bio- physicochemical interactions at play at the interface, we are at a point where the pockets of assembled knowledge are providing a conceptual framework to guide this exploration, and review the impact on future product development. The book is intended as a valuable resource for academics and pharmaceutical scientists working in the field of polymers, polymers materials for drug delivery, drug delivery systems and ophthalmic drug delivery systems, in addition to medical and health care professionals in these areas.
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262.490000 USD

Nano-Biomaterials For Ophthalmic Drug Delivery

Paperback / softback
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Integrated Nano-Biomechanics provides an integrated look into the rapidly evolving field of nanobiomechanics. The book demystifies the processes in living organisms at the micro- and nano-scale through mechanics, using theoretical, computational and experimental means. The book develops the concept of integrating different technologies along the hierarchical structure of biological systems ...
Integrated Nano-Biomechanics
Integrated Nano-Biomechanics provides an integrated look into the rapidly evolving field of nanobiomechanics. The book demystifies the processes in living organisms at the micro- and nano-scale through mechanics, using theoretical, computational and experimental means. The book develops the concept of integrating different technologies along the hierarchical structure of biological systems and clarifies biomechanical interactions among different levels for the analysis of multi-scale pathophysiological phenomena. With a focus on nano-scale processes and biomedical applications, it is shown how knowledge obtained can be utilized in a range of areas, including diagnosis and treatment of various human diseases and alternative energy production. This book is based on collaboration of researchers from a unique combination of fields, including biomechanics, computational mechanics, GPU application, electron microscopy, biology of motile micro-organisms, entomological mechanics and clinical medicine. The book will be of great interest to scientists and researchers involved in disciplines, such as micro- and nano-engineering, bionanotechnology, biomedical engineering, micro- and nano-scale fluid-mechanics (such as in MEMS devices), nanomedicine and microbiology, as well as industries such as optical devices, computer simulation, plant based energy sources and clinical diagnosis of the gastric diseases.
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210.000000 USD

Integrated Nano-Biomechanics

Hardback
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A comprehensive overview of the current research on inflammation and immunopharmacology, with particular attention to the use of anti-inflammatory drugs, this book discusses future trends in this area of pharmacological research. It addresses an audience with basic knowledge in the inflammatory process, immune system and pharmacology. The book meets the ...
Immunopharmacology and Inflammation
A comprehensive overview of the current research on inflammation and immunopharmacology, with particular attention to the use of anti-inflammatory drugs, this book discusses future trends in this area of pharmacological research. It addresses an audience with basic knowledge in the inflammatory process, immune system and pharmacology. The book meets the needs of graduate students, junior and senior researchers and is useful as a source of the most current information for those already working in these fields.
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209.990000 USD

Immunopharmacology and Inflammation

Hardback
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A silent epidemic in the U.S. is imperiling our health: over-medication. Today, one-third of all adults take two or more prescription drugs and half of all seniors take more than five daily. This book--the first of its kind--shows readers how to avoid the dangers of over-medication. The first half of ...
Do You Really Need That Pill?: How to Avoid Side Effects, Interactions, and Other Dangers of Overmedication
A silent epidemic in the U.S. is imperiling our health: over-medication. Today, one-third of all adults take two or more prescription drugs and half of all seniors take more than five daily. This book--the first of its kind--shows readers how to avoid the dangers of over-medication. The first half of the book describes the harmful effects of taking too many drugs, including drug-drug interactions, medication errors, unintentional overdoses, unnecessary medications, made-up illnesses ( restless leg syndrome ), and side effects that actually mimic a new illness. The second half discusses the benefits and harm caused by many of the most popular drugs used to treat diseases such as high blood pressure, diabetes, high cholesterol, acid reflux, depression, and pain. It tells which drugs are really needed, and whether or not they cause side effects. Finally, readers will learn how to discuss their concerns about too many medications with their health care providers, simple ways to make positive lifestyle changes, and when to consider alternative healing approaches. Combining stories of those who have suffered ill effects from taking too many drugs with data from cutting edge medical findings, Do You Really Need to Take That Pill? helps readers realize they can choose different solutions to their health problems.
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15.740000 USD

Do You Really Need That Pill?: How to Avoid Side Effects, Interactions, and Other Dangers of Overmedication

by Jennifer Jacobs
Paperback / softback
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This book focuses primarily on the role of interfacial forces in understanding biological phenomena at the molecular scale. By providing a suitable statistical mechanical apparatus to handle the biomolecular interface, the book becomes uniquely positioned to address core problems in molecular biophysics. It highlights the importance of interfacial tension in ...
Physics at the Biomolecular Interface: Fundamentals for Molecular Targeted Therapy
This book focuses primarily on the role of interfacial forces in understanding biological phenomena at the molecular scale. By providing a suitable statistical mechanical apparatus to handle the biomolecular interface, the book becomes uniquely positioned to address core problems in molecular biophysics. It highlights the importance of interfacial tension in delineating a solution to the protein folding problem, in unravelling the physico-chemical basis of enzyme catalysis and protein associations, and in rationally designing molecular targeted therapies. Thus grounded in fundamental science, the book develops a powerful technological platform for drug discovery, while it is set to inspire scientists at any level in their careers determined to address the major challenges in molecular biophysics. The acknowledgment of how exquisitely the structure and dynamics of proteins and their aqueous environment are related attests to the overdue recognition that biomolecular phenomena cannot be effectively understood without dealing with interfacial behaviour. There is an urge to grasp how biologically relevant behaviour is shaped by the structuring of biomolecular interfaces and how interfacial tension affects the molecular events that take place in the cell. This book squarely addresses these needs from a physicist perspective. The book may serve as a monograph for practitioners and, alternatively, as an advanced textbook. Fruitful reading requires a background in physical chemistry and some basics in biophysics. The selected problems at the end of the chapters and the progression in conceptual difficulty make it a suitable textbook for a graduate level course or an elective course for seniors majoring in chemistry, physics, biomedical engineering or related disciplines.
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188.990000 USD

Physics at the Biomolecular Interface: Fundamentals for Molecular Targeted Therapy

by Ariel Fernandez
Paperback / softback
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Post-Authorization Safety Studies of Medicinal Products: The PASS Book bridges the gap in the literature by providing a complete look at post-authorization safety studies and important pharmacoepidemiology and pharmacovigilance aspects. It covers various types and limitations of active surveillance programs, including the use of large databases and disparate data sources ...
Post-Authorization Safety Studies of Medicinal Products: The PASS Book
Post-Authorization Safety Studies of Medicinal Products: The PASS Book bridges the gap in the literature by providing a complete look at post-authorization safety studies and important pharmacoepidemiology and pharmacovigilance aspects. It covers various types and limitations of active surveillance programs, including the use of large databases and disparate data sources for rapid signal detection, as well as novel and advanced design and analysis approaches for causal interference from observational data. This book serves as an important reference for pharmacovigilance scientists and pharmacoepidemiologists who are searching for the appropriate study design to answer safety research questions. Readers will be able to effectively and efficiently design and interpret findings from post-authorization safety studies with the goal of improving the benefit-risk balance of a drug in order to optimize patient safety.
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131.250000 USD

Post-Authorization Safety Studies of Medicinal Products: The PASS Book

Hardback
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This book covers the essentials of drug delivery research and provides a unique forum for scientific experimental methods that are exclusively focused by the in-vitro, ex-vivo, and in-vivo methodologies of drug delivery research and felicitates translational research. The book includes recent and novel approaches in evaluation methods of transdermal, nasal, ...
In-Vitro and In-Vivo Tools in Drug Delivery Research for Optimum Clinical Outcomes
This book covers the essentials of drug delivery research and provides a unique forum for scientific experimental methods that are exclusively focused by the in-vitro, ex-vivo, and in-vivo methodologies of drug delivery research and felicitates translational research. The book includes recent and novel approaches in evaluation methods of transdermal, nasal, ocular, oral and intraoral, gastro-retentive, colon-targeted, and brain-targeted drug delivery systems. Providing up to date and comprehensive information, this text is invaluable to students, teachers, scientists, and others employed in the field of drug delivery.
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221.81 USD

In-Vitro and In-Vivo Tools in Drug Delivery Research for Optimum Clinical Outcomes

Hardback
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This handbook covers established and advanced techniques for biomarker analysis, such as guidelines and strategies for assay validation methods; different mathematical models that are necessary in contemporary drug discovery and development; and evaluation of new cytometry methods. Expertly curated by two practicing professionals in drug development and biotherapeutics, individual chapters ...
Translating Molecular Biomarkers into Clinical Assays: Techniques and Applications
This handbook covers established and advanced techniques for biomarker analysis, such as guidelines and strategies for assay validation methods; different mathematical models that are necessary in contemporary drug discovery and development; and evaluation of new cytometry methods. Expertly curated by two practicing professionals in drug development and biotherapeutics, individual chapters are selected for novel and sound research; information is chosen based on its relevance to lab applications and clinical trials, such as the topic of selecting animal models for their relevancy to humans. The book is multifaceted, discussing the ethics and issues with biospecimens and providing an in-depth analysis to the differences between pre-clinical and clinical assay development. The book is an essential read for general readers who need an introduction to the history and background of biomarkers, and it also provides critical analyses of various new validation methods for practitioners and researchers.
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209.990000 USD

Translating Molecular Biomarkers into Clinical Assays: Techniques and Applications

Paperback / softback
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The aim of this book is to present a range of analytical methods that can be used in formulation design and development and focus on how these systems can be applied to understand formulation components and the dosage form these build. To effectively design and exploit drug delivery systems, the ...
Analytical Techniques in the Pharmaceutical Sciences
The aim of this book is to present a range of analytical methods that can be used in formulation design and development and focus on how these systems can be applied to understand formulation components and the dosage form these build. To effectively design and exploit drug delivery systems, the underlying characteristic of a dosage form must be understood--from the characteristics of the individual formulation components, to how they act and interact within the formulation, and finally, to how this formulation responds in different biological environments. To achieve this, there is a wide range of analytical techniques that can be adopted to understand and elucidate the mechanics of drug delivery and drug formulation. Such methods include e.g. spectroscopic analysis, diffractometric analysis, thermal investigations, surface analytical techniques, particle size analysis, rheological techniques, methods to characterize drug stability and release, and biological analysis in appropriate cell and animal models. Whilst each of these methods can encompass a full research area in their own right, formulation scientists must be able to effectively apply these methods to the delivery system they are considering. The information in this book is designed to support researchers in their ability to fully characterize and analyze a range of delivery systems, using an appropriate selection of analytical techniques. Due to its consideration of regulatory approval, this book will also be suitable for industrial researchers both at early stage up to pre-clinical research.
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293.990000 USD

Analytical Techniques in the Pharmaceutical Sciences

Paperback / softback
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This book provides an up-to-date review of the general principles of and techniques for confirmatory adaptive designs. Confirmatory adaptive designs are a generalization of group sequential designs. With these designs, interim analyses are performed in order to stop the trial prematurely under control of the Type I error rate. In ...
Group Sequential and Confirmatory Adaptive Designs in Clinical Trials
This book provides an up-to-date review of the general principles of and techniques for confirmatory adaptive designs. Confirmatory adaptive designs are a generalization of group sequential designs. With these designs, interim analyses are performed in order to stop the trial prematurely under control of the Type I error rate. In adaptive designs, it is also permissible to perform a data-driven change of relevant aspects of the study design at interim stages. This includes, for example, a sample-size reassessment, a treatment-arm selection or a selection of a pre-specified sub-population. Essentially, this adaptive methodology was introduced in the 1990s. Since then, it has become popular and the object of intense discussion and still represents a rapidly growing field of statistical research. This book describes adaptive design methodology at an elementary level, while also considering designing and planning issues as well as methods for analyzing an adaptively planned trial. This includes estimation methods and methods for the determination of an overall p-value. Part I of the book provides the group sequential methods that are necessary for understanding and applying the adaptive design methodology supplied in Parts II and III of the book. The book contains many examples that illustrate use of the methods for practical application. The book is primarily written for applied statisticians from academia and industry who are interested in confirmatory adaptive designs. It is assumed that readers are familiar with the basic principles of descriptive statistics, parameter estimation and statistical testing. This book will also be suitable for an advanced statistical course for applied statisticians or clinicians with a sound statistical background.
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146.990000 USD

Group Sequential and Confirmatory Adaptive Designs in Clinical Trials

by Werner Brannath, Gernot Wassmer
Paperback / softback
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Characterization of Nanoparticles Intended for Drug Delivery
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178.490000 USD

Characterization of Nanoparticles Intended for Drug Delivery

Hardback
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Fundamentals of Nuclear Pharmacy
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115.490000 USD

Fundamentals of Nuclear Pharmacy

by Gopal B Saha
Hardback
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This title is a comprehensive text that addresses key aspects of nanomedicine such as properties occurring at the nanoscale that have unique medical effects, great molecular knowledge of the human body and disease processes, and apparent clinical translation as opposed to narrow insufficient texts that address only a few topics ...
Nanomedicine
This title is a comprehensive text that addresses key aspects of nanomedicine such as properties occurring at the nanoscale that have unique medical effects, great molecular knowledge of the human body and disease processes, and apparent clinical translation as opposed to narrow insufficient texts that address only a few topics and attempt to rebrand established drug delivery. It will clearly define the field which is needed due to the immaturity and broad nature of the field. The book is aligned with both the USA and European roadmaps for nanomedicine and will address initiatives taken in Asia that ensures timely and relevant content. In-depth chapters ensure each section is adequately covered. The nanopharmaceutical section focuses on novel drug delivery systems relevant to nanomedicine and the book has an extensive section on immune recognition at the nanoscale which has implications for in vivo applications of nanomedicines.
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230.990000 USD

Nanomedicine

Paperback / softback
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