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Our genome is the blueprint to our existence: it encodes all the information we need to develop from a single cell into a hugely complicated functional organism. But it is more than a static information store: our genome is a dynamic, tightly-regulated collection of genes, which switch on and off ...
Introduction to Genomics
Our genome is the blueprint to our existence: it encodes all the information we need to develop from a single cell into a hugely complicated functional organism. But it is more than a static information store: our genome is a dynamic, tightly-regulated collection of genes, which switch on and off in many combinations to give the variety of cells from which our bodies are formed. But how do we identify the genes that make up our genome? How do we determine their function? And how do different genes form the regulatory networks that direct the processes of life? Introduction to Genomics is a fascinating insight into what can be revealed from the study of genomes: how organisms differ or match; how different organisms evolved; how the genome is constructed and how it operates; and what our understanding of genomics means in terms of our future health and wellbeing. Covering the latest techniques that enable us to study the genome in ever-increasing detail, the book explores what the genome tells us about life at the level of the molecule, the cell, and the organism. Learning features throughout make this book the ideal teaching and learning tool: extensive end of chapter exercises and problems help the student to fully grasp the concepts being presented, while end of chapter weblems (web-based problems) and lab assignments give the student the opportunity to engage with the subject in a hands-on manner. The field of genomics is enabling us to analyze life in more detail than ever before; Introduction to Genomics is the perfect guide to this enthralling subject. Online Resource Centre The Online Resource Centre to accompany Introduction to Genomics features For lecturers: Figures from the book in electronic format For students: Answers to end-of-chapter exercises Guided tour of web sites in genomics Hints to end-of-chapter problems Rotating figures
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78.09 USD

Introduction to Genomics

by Arthur M. Lesk
Paperback
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Magnetic resonance imaging (MRI) has become the leading cross-sectional imaging method in clinical practice. Continuous technical improvements have significantly broadened the scope of applications. At present, MR imaging is not only the most important diagnostic technique in neuroradiology and musculoskeletal radiology, but has also become an invaluable diagnostic tool for ...
Clinical MR Imaging: A Practical Approach
Magnetic resonance imaging (MRI) has become the leading cross-sectional imaging method in clinical practice. Continuous technical improvements have significantly broadened the scope of applications. At present, MR imaging is not only the most important diagnostic technique in neuroradiology and musculoskeletal radiology, but has also become an invaluable diagnostic tool for abdominal, pelvic, cardiac, breast and vascular imaging. This book offers practical guidelines for performing efficient and cost-effective MRI examinations in daily practice. The underlying idea is that, by adopting a practical protocol-based approach, the work-flow in a MRI unit can be streamlined and optimized.
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293.990000 USD

Clinical MR Imaging: A Practical Approach

Hardback
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This is the second edition of a well-received book in the series Drug Discovery and Evaluation The completely revised new edition of the volume reflects the current state of the art in Clinical Pharmacology. Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The ...
Drug Discovery and Evaluation: Methods in Clinical Pharmacology
This is the second edition of a well-received book in the series Drug Discovery and Evaluation The completely revised new edition of the volume reflects the current state of the art in Clinical Pharmacology. Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series Drug Discovery and Evaluation in the form of a recommendation document. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: Methods in Clinical Pharmacology . For the 2nd edition of this volume, the chapters have been revised and completely updated. A large number of assays were added. New chapters were included, such as pain, addiction, gene therapy, orphan diseases.
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839.990000 USD

Drug Discovery and Evaluation: Methods in Clinical Pharmacology

Hardback
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Naturally Occurring Chemicals Against Alzheimer's Disease offers a detailed discussion on the roles, molecular mechanisms, structural activity relationships, toxicology and clinical data on phytochemicals in relation to Alzheimer's disease. The book examines the available phytochemicals and plants that are potentially effective, also determining the role and molecular targets of these ...
Naturally Occurring Chemicals Against Alzheimer's Disease
Naturally Occurring Chemicals Against Alzheimer's Disease offers a detailed discussion on the roles, molecular mechanisms, structural activity relationships, toxicology and clinical data on phytochemicals in relation to Alzheimer's disease. The book examines the available phytochemicals and plants that are potentially effective, also determining the role and molecular targets of these phytochemicals in combating AD. This comprehensive resource will be helpful to researchers who are working on herbal drugs on AD, phytochemistry, pharmacology, toxicology, clinical trials, neuroscience and advancement in formulations.
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236.250000 USD

Naturally Occurring Chemicals Against Alzheimer's Disease

Paperback / softback
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This book, now in an extensively revised second edition, describes the crucial role of zinc signaling in biological processes on a molecular and physiological basis. Global leaders in the field review the latest knowledge, including the very significant advances in understanding that have been achieved since publication of the first ...
Zinc Signaling
This book, now in an extensively revised second edition, describes the crucial role of zinc signaling in biological processes on a molecular and physiological basis. Global leaders in the field review the latest knowledge, including the very significant advances in understanding that have been achieved since publication of the first edition. Detailed information is provided on all the essentials of zinc signaling, covering molecular aspects and the roles of zinc transporters, the zinc sensing receptor, and metallothioneins. Detection techniques for zinc signals, involving genetically encoded and chemical probes, are also described. The critical contributions of the zinc signal in maintaining health and the adverse consequences of any imbalance in the signal are then thoroughly addressed. Here, readers will find up-to-date information on the significance of the zinc signal in a wide range of conditions, including cardiovascular disorders, neurodegenerative diseases, diabetes, autoimmune diseases, inflammatory conditions, skin disease, osteoarthritis, and cancer. The book will be of value for researchers, clinicians, and advanced students.
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262.490000 USD
Hardback
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This book focuses on thoracic ultrasound, a versatile, diagnostically accurate, low-cost, noninvasive and non-ionizing imaging technique. Thanks to portable devices, the method can be used to provide quick and accurate diagnoses in emergency settings, during transport, or at the patient's bedside in intensive care units. In addition, as a dynamic ...
Thoracic Ultrasound and Integrated Imaging
This book focuses on thoracic ultrasound, a versatile, diagnostically accurate, low-cost, noninvasive and non-ionizing imaging technique. Thanks to portable devices, the method can be used to provide quick and accurate diagnoses in emergency settings, during transport, or at the patient's bedside in intensive care units. In addition, as a dynamic examination that allows real-time assessment, it can be used to optimize diagnoses, the use of respiratory support equipment, surgical interventions and physiopathological assessments, both in critical patients and those with chronic conditions. Lastly, since it avoids ionizing radiation, thoracic ultrasound offers a first-line diagnostic tool for thoracic disease assessment in connection with pregnancy, neonatology and pediatrics. Pursuing a practical approach, this book also addresses the technological components that are needed in order to adequately set up the equipment. This integrated approach provides non-radiologists with essential know-how on using thoracic ultrasound as an extension of their physical examinations. Specific chapters are dedicated to thoracic ultrasound applications in neonatology, pediatrics and emergency medicine, as well as guided procedures and diaphragm function studies. Thoracic ultrasound has been a central element in the editors' clinical and experimental work for several years, and the book also includes contributions by prominent international experts on specific applications. Given its content and scope, the book will be of interest to all medical practitioners seeking a practical approach to thoracic ultrasound.
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146.990000 USD
Hardback
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The book is an on-the-spot reference for residents and medical students seeking diagnostic radiology fast facts. Its question-and-answer format makes it a perfect quick-reference for personal review and studying for board examinations and re-certification. Readers can read the text from cover to cover to gain a general foundation of knowledge ...
Essential Radiology Review: A Question and Answer Guide
The book is an on-the-spot reference for residents and medical students seeking diagnostic radiology fast facts. Its question-and-answer format makes it a perfect quick-reference for personal review and studying for board examinations and re-certification. Readers can read the text from cover to cover to gain a general foundation of knowledge that can be built upon through practice or can use choice chapters to review a specific subspecialty before starting a new rotation or joining a new service. With hundreds of high-yield questions and answer items, this resource addresses both general and subspecialty topics and provides accurate, on-the-spot answers. Sections are organized by subspecialty and body area, including chest, abdomen, and trauma, and chapters cover the anatomy, pathophysiology, differential diagnosis, hallmark signs, and image features of major diseases and conditions. Key example images and illustrations enhance the text throughout and provide an ideal, pocket-sized resource for residents and medical students.
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157.490000 USD

Essential Radiology Review: A Question and Answer Guide

Paperback / softback
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This publication is based on peer-reviewed manuscripts from the 2019 Conference on Drug Design & Discovery Technologies (CDDT) held at Ramaiah University of Applied Sciences, India. Providing a wide range of up to date topics on the latest advancements in drug design and discovery technologies, this book ensures the reader ...
Conference on Drug Design and Discovery Technologies
This publication is based on peer-reviewed manuscripts from the 2019 Conference on Drug Design & Discovery Technologies (CDDT) held at Ramaiah University of Applied Sciences, India. Providing a wide range of up to date topics on the latest advancements in drug design and discovery technologies, this book ensures the reader receives a good understanding of the scope of the field. Aimed at scientists, students, regulators, academics and consultants throughout the world, this book is an ideal resource for anyone interested in the state of the art in drug design and discovery.
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183.750000 USD

Conference on Drug Design and Discovery Technologies

Hardback
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This introduction to medical imaging introduces all of the major medical imaging techniques in wide use in both medical practice and medical research, including Computed Tomography, Ultrasound, Positron Emission Tomography, Single Photon Emission Tomography and Magnetic Resonance Imaging. Principles of Medical Imaging for Engineers introduces fundamental concepts related to why ...
Principles of Medical Imaging for Engineers: From Signals to Images
This introduction to medical imaging introduces all of the major medical imaging techniques in wide use in both medical practice and medical research, including Computed Tomography, Ultrasound, Positron Emission Tomography, Single Photon Emission Tomography and Magnetic Resonance Imaging. Principles of Medical Imaging for Engineers introduces fundamental concepts related to why we image and what we are seeking to achieve to get good images, such as the meaning of 'contrast' in the context of medical imaging. This introductory text separates the principles by which 'signals' are generated and the subsequent 'reconstruction' processes, to help illustrate that these are separate concepts and also highlight areas in which apparently different medical imaging methods share common theoretical principles. Exercises are provided in every chapter, so the student reader can test their knowledge and check against worked solutions and examples. The text considers firstly the underlying physical principles by which information about tissues within the body can be extracted in the form of signals, considering the major principles used: transmission, reflection, emission and resonance. Then, it goes on to explain how these signals can be converted into images, i.e., full 3D volumes, where appropriate showing how common methods of 'reconstruction' are shared by some imaging methods despite relying on different physics to generate the 'signals'. Finally, it examines how medical imaging can be used to generate more than just pictures, but genuine quantitative measurements, and increasingly measurements of physiological processes, at every point within the 3D volume by methods such as the use of tracers and advanced dynamic acquisitions. Principles of Medical Imaging for Engineers will be of use to engineering and physical science students and graduate students with an interest in biomedical engineering, and to their lecturers.
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94.490000 USD

Principles of Medical Imaging for Engineers: From Signals to Images

by Michael Chappell
Hardback
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Depite the rapid expansion of the field of biophysics, there are very few books that comprehensively treat specific topics in this area. Recently, the field of single molecule biophysics has developed very quickly, and a few books specifically treating single molecule methods are beginning to appear. However, the promise of ...
Biophysics of DNA-Protein Interactions: From Single Molecules to Biological Systems
Depite the rapid expansion of the field of biophysics, there are very few books that comprehensively treat specific topics in this area. Recently, the field of single molecule biophysics has developed very quickly, and a few books specifically treating single molecule methods are beginning to appear. However, the promise of single molecule biophysics is to contribute to the understanding of specific fields of biology using new methods. This book would focus on the specific topic of the biophysics of DNA-protein interactions, and would include the use of new approaches, including both bulk methods as well as single molecule methods. This would make the book attractive to anyone working in the general area of DNA-protein interactions, which is of course a much wider market than just single molecule biophysicists or even biophysicists. The subject of the book will be the biophysics of DNA-protein interactions, and will include new methods and results that describe the physical mechanism by which proteins interact with DNA. For example, there has been much recent work on the mechanism by which proteins search for specific binding sites on DNA. A few chapters will be devoted to experiments and theory that shed light on this important problem. We will also cover proteins that alter DNA properties to facilitate interactions important for transcription or replication. Another section of the book will cover the biophysical mechanism by which motor proteins interact with DNA. Finally, we will cover larger protein-DNA complexes, such as replication forks, recombination complexes, DNA repair interactions, and their chromatin context.
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146.990000 USD

Biophysics of DNA-Protein Interactions: From Single Molecules to Biological Systems

Paperback / softback
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Animal cell technology aims to understand structures, functions, and behaviors of differentiated animal cells and to ascertain their abilities to be used in industrial and medical purposes. This volume gives readers a complete review of the present state of the art in Japan.
Animal Cell Technology: Challenges for the 21st Century: Proceedings of the joint international meeting of the Japanese Association for Animal Cell Technology (JAACT) and the European Society for Animal Cell Technology (ESACT) 1998, Kyoto, Japan
Animal cell technology aims to understand structures, functions, and behaviors of differentiated animal cells and to ascertain their abilities to be used in industrial and medical purposes. This volume gives readers a complete review of the present state of the art in Japan.
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293.990000 USD

Animal Cell Technology: Challenges for the 21st Century: Proceedings of the joint international meeting of the Japanese Association for Animal Cell Technology (JAACT) and the European Society for Animal Cell Technology (ESACT) 1998, Kyoto, Japan

Hardback
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The 1989 International Conference on Nuclear Analytical Methods in theUfe Scienceswas a continuationofa seriesofconfer- encesheldbytheInternationalAtomicEnergyAgency. Thefirsttook placeinAmsterdamin 1967,thesecondin Bledin 1972,andthethird inViennain 1978. Theaimoftheseconferenceshasbeentostimulate discussions between scientists who are working as biologists, envi- ronmentalists, and physicians, and those who are working on the advancementofnuclear analytical techniques. The 1989 Conference was held ...
Nuclear Analytical Methods in the Life Sciences
The 1989 International Conference on Nuclear Analytical Methods in theUfe Scienceswas a continuationofa seriesofconfer- encesheldbytheInternationalAtomicEnergyAgency. Thefirsttook placeinAmsterdamin 1967,thesecondin Bledin 1972,andthethird inViennain 1978. Theaimoftheseconferenceshasbeentostimulate discussions between scientists who are working as biologists, envi- ronmentalists, and physicians, and those who are working on the advancementofnuclear analytical techniques. The 1989 Conference was held at the National Institute of Standards and Technology (NIST, formerly the National Bureau of Standards)inGaithersburg,Maryland. ThefocalpointoftheConfer- ence was the presentation of results from multidisciplinary research involvingnuclear analytical techniques and their applications to the life sciences. Wehave obtained contributions from life sciencefields thatrelatethenuclear analyticalmethods to abroad scopeofbiologi- cal, medical,and environmental applications. Deliberately,our defi- nition of nuclear analytical techniques was made flexible. Methods and applications were treated in a more comprehensive way than thoseatestablished meetings. Particularconsideration was given to contributions from developing countries. We are indebted to many people and organizations for their assistancein making this symposium possible. TheConference was organizedbytheUSDepartmentofCommerce'sNISTincooperation with the International Atomic Energy Agency, by supplying both financial support and scientific expertise. The meeting was cospon- soredbytheAmericanNuclearSociety,theUSDepartmentofEnergy, andtheFoodandDrugAdministration,whoprovidedbothorganiza- tional and financial support. We hope that the results of this Conference, presented here, will stimulatethe developmentofnew collaborativeresearch efforts betweenthe life sciencesand analytical fields. Acontinuationofthis series ofconferences willbe a measureofthe successofthis interdis- ciplinary collaboration.
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282.450000 USD

Nuclear Analytical Methods in the Life Sciences

by Vincent P. Guinn, Rolf Zeisler
Hardback
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The colony-stimulating factors (CSFs) are the major regulators in the body of the production and activity of two types of white blood cells - granulocytes and macrophages. This book provides a detailed account of the discovery of the CSFs, their structure, molecular biology and cellular receptors, the biology of the ...
The Hemopoietic Colony-stimulating Factors: From Biology to Clinical Applications
The colony-stimulating factors (CSFs) are the major regulators in the body of the production and activity of two types of white blood cells - granulocytes and macrophages. This book provides a detailed account of the discovery of the CSFs, their structure, molecular biology and cellular receptors, the biology of the CSFs in vivo and in vitro and their present and future clinical applications. Written by two of the pioneers in the discovery of CSFs, it is a clear and well-illustrated survey of the history, knowledge and future directions of this exciting field of investigation, and serves also as a guide to the more general areas of growth factor and cytokine research. It will prove an invaluable review for cell biologists interested in how growth factors act on the body, as well as for clinicians applying the fruits of modern biotechnology to improved patient care.
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166.940000 USD

The Hemopoietic Colony-stimulating Factors: From Biology to Clinical Applications

by Anthony Nicola Nicos, Donald Metcalf
Hardback
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Recent developments in stem cell biology have opened new directions in cell therapy. This book provides the state-of-the-art developments in using biomaterials as artificial niches for engineering stem cells, both for the purpose of better understanding their biology under 3D biomimetic conditions as well as for developing new strategies for ...
Biomaterials as Stem Cell Niche
Recent developments in stem cell biology have opened new directions in cell therapy. This book provides the state-of-the-art developments in using biomaterials as artificial niches for engineering stem cells, both for the purpose of better understanding their biology under 3D biomimetic conditions as well as for developing new strategies for efficient long term maintenance and directed differentiation of stem cells into various therapeutic lineages. Animal and human stem cells of both embryonic and adult origin are discussed with applications ranging from nerve regeneration, orthopedics, cardiovascular therapy, blood cell generation and cancer therapy. Both synthetic and natural biomaterials are reviewed with emphasis on how material-stem cell interactions direct specific signaling pathways and ultimately modulate the cell fate. This book is valuable for biomaterial scientists, tissue engineers, clinicians as well as stem cell biologists involved in basic research and applications of adult and embryonic stem cells.
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230.990000 USD

Biomaterials as Stem Cell Niche

Hardback
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Hematopathology: Genomic Mechanisms of Neoplastic Diseases will keep physicians abreast of the rapid and complex changes in genomic medicine, as exemplified by the molecular pathology of hematologic malignancies. This timely volume will update physicians on the complexities of genomic lesions, as well as offer an integrated framework encompassing molecular diagnosis, ...
Hematopathology: Genomic Mechanisms of Neoplastic Diseases
Hematopathology: Genomic Mechanisms of Neoplastic Diseases will keep physicians abreast of the rapid and complex changes in genomic medicine, as exemplified by the molecular pathology of hematologic malignancies. This timely volume will update physicians on the complexities of genomic lesions, as well as offer an integrated framework encompassing molecular diagnosis, the new WHO classification of hematologic neoplasms with focus on molecular pathology, prognostic value of molecular tests, and molecular monitoring of response to gene-targeted therapy. As such, it will be of great value to hematologists, oncologists, pathologists, internal medicine and pediatric specialists, as well as bioscientific staff and laboratorians in private hospitals and academic institutions.
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262.490000 USD

Hematopathology: Genomic Mechanisms of Neoplastic Diseases

Paperback / softback
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Although lots of books have been published about herbal therapy, a comprehensive overview of the adverse effects of botanical medicines is not available. Yet such an overview is badly needed, because of the enormous rise in the use of herbal remedies. The book series will provide approximately 150 monographs on ...
Adverse Effects of Herbal Drugs 2
Although lots of books have been published about herbal therapy, a comprehensive overview of the adverse effects of botanical medicines is not available. Yet such an overview is badly needed, because of the enormous rise in the use of herbal remedies. The book series will provide approximately 150 monographs on herbal remedies and plant-derived drugs. Each monograph will provide introductory information on Botany, Chemistry, Pharmacology and Uses, followed by an Adverse Reaction Profile subdivided according to organ and function. The World Health Organization Regional Office for Europe (Copenhagen) has decided to support the book in the form of an acknowledgement that it has been preparedin cooperation with this Office.
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146.990000 USD

Adverse Effects of Herbal Drugs 2

by H. J. Woerdenbag, H. Winterhoff, Jennifer J. Westendorf, U. Sonnenborn, Rudolf Hansel, Peter A. G. M. de Smet, I. J. Cubbin, D., Corrigan, I. H. Bowen
Paperback / softback
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Fluorescent proteins are intimately connected to research in the life sciences. Tagging of gene products with fluorescent proteins has revolutionized all areas of biosciences, ranging from fundamental biochemistry to clinical oncology, to environmental research. The discovery of the Green Fluorescent Protein, its first, seminal application and the ingenious development of ...
Fluorescent Proteins II: Application of Fluorescent Protein Technology
Fluorescent proteins are intimately connected to research in the life sciences. Tagging of gene products with fluorescent proteins has revolutionized all areas of biosciences, ranging from fundamental biochemistry to clinical oncology, to environmental research. The discovery of the Green Fluorescent Protein, its first, seminal application and the ingenious development of a broad palette of fluorescence proteins of other colours, was consequently recognised with the Nobel Prize for Chemistry in 2008. Fluorescent Proteins II highlights the physicochemical and biophysical aspects of fluorescent protein technology beyond imaging. It is tailored to meet the needs of physicists, chemists and biologists who are interested in the fundamental properties of fluorescent proteins, while also focussing on specific applications. The implementations described are cutting-edge studies and exemplify how the physical and chemical properties of fluorescent proteins can stimulate novel findings in life sciences.
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367.490000 USD

Fluorescent Proteins II: Application of Fluorescent Protein Technology

Hardback
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From humble beginnings over 25 years ago as a lipid kinase activity associated with certain oncoproteins, PI3K (phosphoinositide 3-kinase) has been catapulted to the forefront of drug development in cancer, immunity and thrombosis, with the first clinical trials of PI3K pathway inhibitors now in progress. Here we give a brief ...
Phosphoinositide 3-kinase in Health and Disease: Volume 1
From humble beginnings over 25 years ago as a lipid kinase activity associated with certain oncoproteins, PI3K (phosphoinositide 3-kinase) has been catapulted to the forefront of drug development in cancer, immunity and thrombosis, with the first clinical trials of PI3K pathway inhibitors now in progress. Here we give a brief overview of some key discoveries in the PI3K area and their impact, and include thoughts on the current state of the field, and where it could go from here
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293.990000 USD

Phosphoinositide 3-kinase in Health and Disease: Volume 1

Hardback
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Fluorescent proteins are intimately connected to research in the life sciences. Tagging of gene products with fluorescent proteins has revolutionized all areas of biosciences, ranging from fundamental biochemistry to clinical oncology, to environmental research. The discovery of the Green Fluorescent Protein, its first, seminal application and the ingenious development of ...
Fluorescent Proteins I: From Understanding to Design
Fluorescent proteins are intimately connected to research in the life sciences. Tagging of gene products with fluorescent proteins has revolutionized all areas of biosciences, ranging from fundamental biochemistry to clinical oncology, to environmental research. The discovery of the Green Fluorescent Protein, its first, seminal application and the ingenious development of a broad palette of fluorescence proteins of other colours, was consequently recognised with the Nobel Prize for Chemistry in 2008. Fluorescent Proteins I is devoted to the basic photophysical and photochemical aspects of fluorescent protein technology. Experienced experts highlight colour tuning, the exploration of switching phenomena and respective methods for their investigation. The book provides a thorough understanding of primary molecular processes allowing the design of fluorescent proteins for specific applications.
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314.990000 USD

Fluorescent Proteins I: From Understanding to Design

Paperback / softback
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The book covers the totality of bilirubin (and heme from which bilirubin is derived biogenetically) the structural relationship of bilirubin to its solution properties and metabolism and to phototherapy for the jaundiced newborn - a common medical procedure used nowadays for lowering serum bilirubin, which is neurotoxic.
Bilirubin: Jekyll and Hyde Pigment of Life: Pursuit of its Structure Through Two World Wars to the New Millenium
The book covers the totality of bilirubin (and heme from which bilirubin is derived biogenetically) the structural relationship of bilirubin to its solution properties and metabolism and to phototherapy for the jaundiced newborn - a common medical procedure used nowadays for lowering serum bilirubin, which is neurotoxic.
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524.990000 USD

Bilirubin: Jekyll and Hyde Pigment of Life: Pursuit of its Structure Through Two World Wars to the New Millenium

by David A. Lightner
Hardback
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This unique text/reference discusses in depth the two integral components of reconstructive surgery; fracture detection, and reconstruction from broken bone fragments. In addition to supporting its application-oriented viewpoint with detailed coverage of theoretical issues, the work incorporates useful algorithms and relevant concepts from both graph theory and statistics. Topics and ...
Computer Vision-Guided Virtual Craniofacial Surgery: A Graph-Theoretic and Statistical Perspective
This unique text/reference discusses in depth the two integral components of reconstructive surgery; fracture detection, and reconstruction from broken bone fragments. In addition to supporting its application-oriented viewpoint with detailed coverage of theoretical issues, the work incorporates useful algorithms and relevant concepts from both graph theory and statistics. Topics and features: presents practical solutions for virtual craniofacial reconstruction and computer-aided fracture detection; discusses issues of image registration, object reconstruction, combinatorial pattern matching, and detection of salient points and regions in an image; investigates the concepts of maximum-weight graph matching, maximum-cardinality minimum-weight matching for a bipartite graph, determination of minimum cut in a flow network, and construction of automorphs of a cycle graph; examines the techniques of Markov random fields, hierarchical Bayesian restoration, Gibbs sampling, and Bayesian inference.
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145.950000 USD

Computer Vision-Guided Virtual Craniofacial Surgery: A Graph-Theoretic and Statistical Perspective

by Suchendra M. Bhandarkar, Ananda S. Chowdhury
Hardback
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As age related diseases increase in prevalence and impact more significantly on medical resources it is imperative to understand these diseases and the mechanisms behind their progression. New research has stimulated a growing interest in mitochondrial involvement in neurodegenerative disorders such as Parkinson's disease, Alzheimer's disease and multiple sclerosis and ...
Mitochondrial Dysfunction in Neurodegenerative Disorders
As age related diseases increase in prevalence and impact more significantly on medical resources it is imperative to understand these diseases and the mechanisms behind their progression. New research has stimulated a growing interest in mitochondrial involvement in neurodegenerative disorders such as Parkinson's disease, Alzheimer's disease and multiple sclerosis and the mechanisms which lead from mitochondrial dysfunction to neurodegeneration. Mitochondrial Dysfunction in Neurodegenerative Disorders brings together contributions from leaders in the field internationally on the various ways in which mitochondrial dysfunction contributes to the pathogenesis of these diseases, guiding the reader through the basic functions of mitochondria and the mechanisms that lead to their dysfunction, to the consequences of this dysfunction on neuronal function before finishing with the modelling of these disorders and discussion of new potential therapeutic targets. Mitochondrial Dysfunction in Neurodegenerative Disorders provides an accessible, authoritative guide to this important area for neurologists; research and clinical neuroscientists; neuropathologists; and residents with an interest in clinical research.
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111.71 USD
Hardback
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Information Processing in Medical Imaging: Proceedings of the 9th conference, Washington D.C., 10-14 June 1985
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83.990000 USD

Information Processing in Medical Imaging: Proceedings of the 9th conference, Washington D.C., 10-14 June 1985

Paperback / softback
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The subject for a volume on the fat-soluble vitamins needs no justification considering the importance of this group of nutrients and the rate of expan sion of our knowledge of its role in cell biology, genetics, and disease. The level of our understanding has clearly moved from knowing what fat ...
Fat-Soluble Vitamins
The subject for a volume on the fat-soluble vitamins needs no justification considering the importance of this group of nutrients and the rate of expan sion of our knowledge of its role in cell biology, genetics, and disease. The level of our understanding has clearly moved from knowing what fat soluble vitamins do to how they perform their functions. Hand in hand with a knowledge of their molecular mechanisms of action is the recognition that vitamins are used sparingly, and regeneration processes operate in certain cases to recycle vitamins from their metabolites. We have divided the volume into alphabetical sections beginning with vitamin A and the carotenoids through vitamins D, E, F, and K, and ending with coenzyme Q. The contributors are all acknowledged experts in their particular fields and have made significant contributions to published research results. All have worked assiduously to deliver the product of their labors on a restricted time scale and to provide the most up-to date information on their respective topics. We are truly grateful for their indulgence.
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209.990000 USD

Fat-Soluble Vitamins

Paperback / softback
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Despite the fact that images constitute the main objects in computer vision and image analysis, there is remarkably little concern about their actual definition. In this book a complete account of image structure is proposed in terms of rigorously defined machine concepts, using basic tools from algebra, analysis, and differential ...
Image Structure
Despite the fact that images constitute the main objects in computer vision and image analysis, there is remarkably little concern about their actual definition. In this book a complete account of image structure is proposed in terms of rigorously defined machine concepts, using basic tools from algebra, analysis, and differential geometry. Machine technicalities such as discretisation and quantisation details are de-emphasised, and robustness with respect to noise is manifest. From the foreword by Jan Koenderink: `It is my hope that the book will find a wide audience, including physicists - who still are largely unaware of the general importance and power of scale space theory, mathematicians - who will find in it a principled and formally tight exposition of a topic awaiting further development, and computer scientists - who will find here a unified and conceptually well founded framework for many apparently unrelated and largely historically motivated methods they already know and love. The book is suited for self-study and graduate courses, the carefully formulated exercises are designed to get to grips with the subject matter and prepare the reader for original research.'
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261.450000 USD

Image Structure

by Luc Florack
Paperback / softback
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This book is devoted to the study of variational methods in imaging. The presentation is mathematically rigorous and covers a detailed treatment of the approach from an inverse problems point of view. Many numerical examples accompany the theory throughout the text. It is geared towards graduate students and researchers in ...
Variational Methods in Imaging
This book is devoted to the study of variational methods in imaging. The presentation is mathematically rigorous and covers a detailed treatment of the approach from an inverse problems point of view. Many numerical examples accompany the theory throughout the text. It is geared towards graduate students and researchers in applied mathematics. Researchers in the area of imaging science will also find this book appealing. It can serve as a main text in courses in image processing or as a supplemental text for courses on regularization and inverse problems at the graduate level.
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89.240000 USD

Variational Methods in Imaging

by Frank Lenzen, Markus Haltmeier, Harald Grossauer, Markus Grasmair, Otmar Scherzer
Paperback / softback
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The Springer Handbook of Enzymes provides concise data on some 5,000 enzymes sufficiently well characterized - and here is the second, updated edition. Their application in analytical, synthetic and biotechnology processes as well as in food industry, and for medicinal treatments is added. Data sheets are arranged in their EC-Number ...
Class 2 Transferases XI: EC 2.7.6 - 2.7.7
The Springer Handbook of Enzymes provides concise data on some 5,000 enzymes sufficiently well characterized - and here is the second, updated edition. Their application in analytical, synthetic and biotechnology processes as well as in food industry, and for medicinal treatments is added. Data sheets are arranged in their EC-Number sequence. The new edition reflects considerable progress in enzymology: the total material has more than doubled, and the complete 2nd edition consists of 39 volumes plus Synonym Index. Starting in 2009, all newly classified enzymes are treated in Supplement Volumes.
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419.990000 USD

Class 2 Transferases XI: EC 2.7.6 - 2.7.7

Hardback
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As a technology, bone densitometry is really quite extraordinary. The ability to quantify the density of the bones at a variety of skeletal sites has truly revolutionized the approach to a number of diseases, the most important of which is osteoporosis. Using the information from the machines, especially dual-energy X ...
Bone Densitometry for Technologists
As a technology, bone densitometry is really quite extraordinary. The ability to quantify the density of the bones at a variety of skeletal sites has truly revolutionized the approach to a number of diseases, the most important of which is osteoporosis. Using the information from the machines, especially dual-energy X ray absortiometry (DXA) technology, physicians can recommend and prescribe interventions that will slow bone loss and reduce the risk of disabling fractures. The remarkable advances in skeletal imaging with densitometry devices have made possible quantitative and diagnostic assessments of skeletal structure. However it is in fact the skill and concern of the technologist that enables all of this to happen. In this updated and expanded third edition of their gold standard and highly praised Bone Densitometry for Technologists, Sydney Lou Bonnick, MD, FACP, and Lori Ann Lewis, MRT, CDT, again offer the most comprehensive review of the standards and developments in the field. Here radiologic technologists, nurse practitioners, physician assistants, and dedicated densitometry technologists can find not only the state-of-the-art guidelines for bone density testing, but also a wide range of other topics, including several new chapters. These include a new chapter on the performance of DXA lumbar spine, proximal femur and forearm studies; one on Using Absolute Risk to Predict Fracture Risk in Clinical Practice; and another providing examples of highly instructional DXA images in which artifacts or structural changes can be seen. There are 2 new appendices and the other 10 appendices from the previous edition have been updated wherever necessary to reflect the most current information available. In Appendix XII, the contents of the accompanying CD-ROM are reviewed. On this CD, readers will find the Precision Calculator Companion that was first included with the 2nd edition of Dr. Bonnick's title, Bone Densitometry in Clinical Practice. Questionnaires designed to capture essential information to utilize FRAX for both men and women are also included on the CD. These questionnaires can be persomalized to better suit a practice's needs. Finally, a continuing education review is also found on the CD, which, if successfully completed, will result in the awarding of 16 hours of Category A credit acceptable to the American Society of Radiologic Technologists.
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124.950000 USD

Bone Densitometry for Technologists

by Lori Ann Lewis, Sydney Lou Bonnick
Hardback
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The chapters of this book report cutting-edge research on molecular events in adiposity and type 2 diabetes, thus opening the way for innovative drug-based therapeutic strategies. It addresses all those who wish to keep in touch with recent developments in the field.
Diabetes - Perspectives in Drug Therapy
The chapters of this book report cutting-edge research on molecular events in adiposity and type 2 diabetes, thus opening the way for innovative drug-based therapeutic strategies. It addresses all those who wish to keep in touch with recent developments in the field.
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524.990000 USD

Diabetes - Perspectives in Drug Therapy

Paperback
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Imaging and Focal Therapy of Early Prostate Cancer evaluates the scientific evidence for the evolving trend to treat low to intermediate risk, clinically localized prostate cancer in a focally ablative manner with novel gland-preserving, focal therapy methods. Various ablative devices such as high intensity focused ultrasound, irreversible electroporation, photodynamic therapy, ...
Imaging and Focal Therapy of Early Prostate Cancer
Imaging and Focal Therapy of Early Prostate Cancer evaluates the scientific evidence for the evolving trend to treat low to intermediate risk, clinically localized prostate cancer in a focally ablative manner with novel gland-preserving, focal therapy methods. Various ablative devices such as high intensity focused ultrasound, irreversible electroporation, photodynamic therapy, cryotherapy and laser ablation, among others, are discussed in regard to their strengths and limitations as a therapeutic modality. Emphasis is placed on tumor stage shift towards early stage disease with an increase in unilateral versus bilateral cancers validated by final pathology assessment of large prostatectomy series. Current and new approaches to image cancer foci within the prostate (3-Dimensional contrast-enhanced transrectal ultrasonography, multiparametric magnetic resonance image with spectroscopy, ETC) are presented along with biopsy techniques to map prostate cancer. Patient selection, treatment strategy, outcomes and safety concerns that may provide acceptable cancer control and improved quality of life for patients are all covered in detail. Written by experts in the field and lavishly illustrated with detailed line-art and photographs, Imaging and Focal Therapy of Early Prostate Cancer is a resourceful volume beneficial to practitioners specializing in the treatment and management of prostate cancer.
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119.70 USD
Hardback
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