Separation Methods in Drug Synthesis and Purification: Volume 8

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Separation Methods in Drug Synthesis and Purification, Second Edition provides an updated overview of the analytical techniques used in drug synthesis and purification. Unlike other books on either separation science or drug synthesis, this volume brings the two together to explain the basic principles and comparisons of each separation technique as it applies specifically to drug synthesis and purification. In the past 17 years separation sciences have gone through significant developments. Several new chapters cover areas that have been developed and were not discussed in the first edition. New to the second edition: Enantiomer separation using capillary electrophoresis (CE) and capillary electro- chromatography (CEC) Computer simulation of chromatographic separation for accelerating method development The application of chromatography and capillary electrophoresis used as surrogates for biological processes Developments in the established techniques of chromatography, particularly in the optimization of separation methods, such as gradient, interfaces to detectors and preparative methods