The University of Illinois College of Medicine has its origins in the 1882 opening of the College of Physicians and Surgeons of Chicago. In 1897 the College of Physicians and Surgeons became affiliated with the University of Illinois and began a relationship that endured its fair share of trials, successes, and even a few bitter fights. In this fact-filled volume, Winton U. Solberg places the early history of the University of Illinois College of Medicine in a national and international context, tracing its origins, crises, and reforms through its first tumultuous decades. Solberg discusses the role of the College of Medicine and the city of Chicago in the historic transformation from the late nineteenth century, when Germany was the acknowledged world center of medicine and the germ theory of disease was not yet widely accepted, to 1920, by which time the United States had emerged as the leader in modern medical research and education. With meticulous scholarship and attention to detail, this volume chronicles the long and difficult struggle to achieve that goal.