This major textbook guides the reader through the basic definitions, fundamentals of design, and techniques of quantitative research. After an initial discussion on the nature of quantitative nursing research, the author explores research questions, hypotheses, causality, generalizability, and randomization. He then considers ethical issues in nursing research. After examining research designs, techniques for data gathering and analysis, and specialized techniques in quantitative research, the author proceeds to discuss the measurement of change, strategies for coping with missing data problems, and the dissemination of research results. Numerous examples, guides for further reading, and exercises to help the reader navigate the research literature are particular features of this textbook.