Research into novel techniques for LC/MS continues to be a lively field, most notably regarding electrospray ionization and atmospheric pressure chemical ionization for analysis of lipids. This growing interest precipitated publication of this volume. A valuable reference and resource, Modern Methods is essential for those interested in moving into the field of lipid analysis using modern instrumentation. It describes previous work that helped establish the foundation of the discipline and demonstrates new data that is quickly defining a new level of state-of-the-art. Described herein are the methods that will be applied to lipids into the next decade and hopefully beyond.