Siting of nuclear reactors has to consider topography, accessibility, infrastructure for transportation, construction facilities, township for staff, feasibility of power evacuation, and availability of cooling water, along with other important safety aspects related to geology, seismology, and meteorology. This book reviews the technical issues presented by metropolitan siting and looks at global trends. It includes a case study on the siting of a reactor in Singapore, which, because of its size and geographic location, provides the most stringent conditions on metropolitan siting.