A current review of basic research on Rickettsiales biology and pathogenesis in one comprehensive volume. * Details the scientific knowledge about how these obligate intracellular bacteria invade, survive and replicate inside eukaryotic cells. * Describes the spectrum of disease caused by an infection including protective and pathologic immune responses. * Describes the latest developments, including genomics and biomathematical modeling, and progress towards genetic tools and a vaccine. * Serves as a significant research book for scientists, physicians, medical students, public health professionals, epidemiologists, biocomputational scientists and government policy makers. This title is published by the American Society of Microbiology Press and distributed by Taylor and Francis in rest of world territories.