At the heart of Houston stands the Texas Medical Center. This dense complex of educational, clinical, and hospital facilities offers state-of-the-art patient care, basic science, and applied research in more than fifty medicine-related institutions. Three medical schools, four schools of nursing, and schools of dentistry, public health, and pharmacology occupy the thousand-acre campus. But none of this would exist if not for the generosity and vision of Monroe Dunaway Anderson, who, in 1936, established the foundation that bears his name. The M. D. Anderson Foundation ultimately became the driving force behind creating and shaping this leading-edge medical complex into what it is today. Enduring Legacy: The M. D. Anderson Foundation and the Texas Medical Center provides a unique perspective on the indispensable role the foundation played in the creation of the Texas Medical Center. It also offers a case study of how public and private institutions worked together to create this veritable city of health that has since become the largest medical complex in human history. Historian William Henry Kellar caps off a decade of research on institutions and characters associated with the Texas Medical Center. He draws on oral histories, extensive archival work, and a growing secondary literature to provide an absorbing account of this leading institution of modern medicine and the philanthropy that made it possible.